Chinese Optics Letters, 2007, 5 (2): 105, Published Online: Feb. 8, 2007
Raman spectroscopy of Chinese human skin in vivo Download: 587次
医用光学 组织光学 中国人 活体皮肤 快速拉曼光谱 检测装置 CCD 光纤 300.6450 Spectroscopy, Raman 170.5660 Raman spectroscopy 170.0170 Medical optics and biotechnology 120.4640 Optical instruments
Abstract
A novel and compact near-infrared (NIR) Raman system is developed using 785-nm diode laser, volume-phase technology (VPT) holographic system, and NIR intensified charge-coupled device (CCD). Signal-to-noise ratio (SNR) and resolution are improved compared with ordinary acquisition method by a specially designed optical fiber detector and the spectrograph image aberration correction with a parabolic-line fiber array. In 1-5 s, Raman spectra of different parts of Chinese human skin are acquired. Autofluorescence is subtracted from the raw spectrum by polynomial fitting and skin Raman spectrum is then smoothed for further analysis.
Yongzeng Li, Rong Chen, Haishan Ceng, Zhiwei Huang, Shangyuan Feng, Shusen Xie. Raman spectroscopy of Chinese human skin in vivo[J]. Chinese Optics Letters, 2007, 5(2): 105.