中国激光, 2004, 31 (2): 249, 网络出版: 2006-06-12
氦氖激光对鼠体液免疫因子IL-2影响的实验研究
Study on the Effects of He-Ne Laser Irradiation on the Activity of Humoral Immune Factors IL-2 in Mice
免疫病理学 氦氖激光照射 免疫调节效应 小鼠 脾淋巴细胞IL-2诱生活性 immunity nosology He-Ne laser irradiation immune modulation mice splenic T lymphocytes induced IL-2 activity
摘要
为探讨氦氖激光照射对小鼠脾淋巴细胞IL-2诱生活性的影响,以BALB/c小鼠为研究对象,应用7.33,11.00,14.67,22.00和36.67 J/cm2 5种剂量的氦氖激光作小鼠内眼角照射,连续照射8天,并于照射开始后第3,6,9,13和17天动态监测实验鼠脾淋巴细胞IL-2诱生活性.结果表明,以日剂量为7.33,11.00,14.67和22.00 J/cm2氦氖激光照射小鼠后,IL-2活性出现不同程度的增强或升高,而36.67 J/cm2剂量组却呈现降低趋势.由此可见,适当剂量的低能量激光照射可对小鼠IL-2诱生活性产生增强效应,而过大剂量氦氖激光照射则对IL-2诱生活性产生抑制效应.
Abstract
In order to illustrate mechanism of the immune modulation effect of He-Ne laser irradiation with the concentration changes of splenic T lymphocytes induced IL-2 activity in mice, the effects of He-Ne laser irradiation on splenic T lymphocytes induced IL-2 activity in mice were studied. By irradiating upon the inner corners of the mice eyes with He-Ne laser at five different dosages of 7 33, 11 00, 14 67, 22 00 and 36 67 J/cm 2 for eight days,the splenic T lymphocytes induced IL-2 activity was monitored...
黄保续, 王洪斌, 刘焕奇, 曲志娜, 刘西锋, 程绍辉, 高利. 氦氖激光对鼠体液免疫因子IL-2影响的实验研究[J]. 中国激光, 2004, 31(2): 249. 黄保续, 王洪斌, 刘焕奇, 曲志娜, 刘西锋, 程绍辉, 高利. Study on the Effects of He-Ne Laser Irradiation on the Activity of Humoral Immune Factors IL-2 in Mice[J]. Chinese Journal of Lasers, 2004, 31(2): 249.