光学与光电技术, 2004, 2 (6): 34, 网络出版: 2006-05-22
关于PDT光敏剂敏化效应光谱及其量子产率的研究
Studies on Sensitized Effect Properties and Quantum Yield of PDT Photosensitizer
竹红菌甲素 光敏剂 单态氧 量子产率 光动力治疗 Hyporcrellin A photosensitizer singlet oxygen quantum yield photodynamic therapy
摘要
从实验的角度研究了HA光敏剂激发态的敏化特性,建立了单态氧量子产率在近红外区的荧光光谱测量系统,测定了HA光敏剂的单态氧量子产率为0.78.结果表明,该类光敏剂具有较强的敏化效应,是一类有前途的光动力治疗(PDT)候选光敏剂.
Abstract
The equipment of measuring fluorescence spectrum in near infrared and quantum yield for singlet molecule oxygen produced by photosensitization is developed. The emission spectra from singlet molecule oxygen in the excited state, ?g, photosensitized by HA in organic solvents are obtained on the equipment. The spectroscopic technology for 1 measuring singlet oxygen fluorescence in near about 1270nm is an advantageous and reliable method for measurement of quantum yield of singlet oxygen sensitized by photosensitizer Hyporcrellin A.
高博文, 赵景秀, 高仲合, 祝永志, 陈平, 汤国庆. 关于PDT光敏剂敏化效应光谱及其量子产率的研究[J]. 光学与光电技术, 2004, 2(6): 34. 高博文, 赵景秀, 高仲合, 祝永志, 陈平, 汤国庆. Studies on Sensitized Effect Properties and Quantum Yield of PDT Photosensitizer[J]. OPTICS & OPTOELECTRONIC TECHNOLOGY, 2004, 2(6): 34.