光子学报, 2005, 34 (2): 315, 网络出版: 2006-06-12
基于紫外吸收光谱的血浆泄漏监测系统的研究
Development of Plasma Leakage Detecting System Based on Ultraviolet Absorption Spectrum
紫外吸收光谱 光电检测 血液循环治疗 血浆泄漏 动态监测 Ultraviolet absorption spectrum Optoelectronic detecting Blood circle treatment Plasma leakage Dynamically monitoring
摘要
介绍了血液体外循环治疗仪工作原理.对含不同浓度血浆的血液体外循环治疗仪废弃液进行了紫外吸收光谱的实验研究,发现此混合液在278nm左右存在明显的吸收峰.在血浆紫外吸收光谱的实验基础上,开发出了与血液体外循环治疗仪配套的血浆泄漏监测系统.血浆浓度在0~0.06ml/ml连续变化的废弃液的监测实验结果表明此系统具有较高的灵敏度.在血浆浓度为0ml/ml、0.015ml/ml、0.03ml/ml时的连续监测实验结果显示此系统具有良好的稳定性.结论表明基于紫外吸收光谱的血浆泄漏监测系统用于血液体外循环治疗仪治疗过程中的血浆泄漏监测是完全可靠的.
Abstract
Blood circle treatment is a new remedy developed for reducing low density lipoprotein and endotoxin of patients′ plasma, consequently, curing or alleviating cardiovascular and cerebrovascular diseases, hypertension and inflammation. However, for there is possibility of plasma leakage before the treated blood is transmitted back to patient and some monitoring procedure is to be maintained. The approach to monitor plasma leakage was presented after a brief introducing of the working principle of the blood circle treatment apparatus. Experiments on ultraviolet absorption spectrum of waste solution of the blood circle treatment apparatus mixed with plasma of different concentration were carried out and, the conclusion that such a solution has an absorption peak at about 278 nm was made. A set of detecting system of plasma leakage suited for the blood circle treatment apparatus was developed with the base of ultraviolet absorption spectrum experiments. In the set double beam scheme was utilized for the optical des
饶程, 邹建, 蔡绍皙, 袁祥辉. 基于紫外吸收光谱的血浆泄漏监测系统的研究[J]. 光子学报, 2005, 34(2): 315. 饶程, 邹建, 蔡绍皙, 袁祥辉. Development of Plasma Leakage Detecting System Based on Ultraviolet Absorption Spectrum[J]. ACTA PHOTONICA SINICA, 2005, 34(2): 315.