将荧光光谱方法应用于具有三种颜色的白癜风皮肤特性的研究, 在对荧光测量以及皮肤组织病理检查的基础上, 建立了三色白癜风皮肤的光学模型, 分析了皮肤黑色素的含量与分布, 并进行了蒙特卡罗计算, 其结果与实测结果基本一致。研究表明:具有三种颜色的白癜风皮肤可作为一个较好的皮肤黑色素含量与分布的模型; 荧光光谱法可以探测到皮肤较深层(真皮层)的黑色素分布或其他组织光学特性; 所建立的白癜风皮肤的光学模型及建模方法, 所采用的光谱比率法等可以在皮肤光学的其他研究中应用。

Fluorescent spectrum was used to study the property of trichrome vitiligo skin. Melanin content and distribution were analyzed and optical model was developed based on the measurement of skin fluorescence and study of skin pathology. Monte Carlo simulation based on this optical model shows good agreement with the experimental result. The study suggests that, trichrome vitiligo skin is an ideal model to study skin melanin content and distribution; fluorescence spectrum can be used to study melanin distribution or other tissue properties in deeper skin (e.g. dermis); the optical model developed and the method to develop it, as well as the spectrum ratio method, can be used in other study of skin optics.