Chinese Journal of Lasers B, 1992, 1 (4): 379, 网络出版: 2007-09-11
DNA damage induced by laser-hematoporphyrin derivative
DNA damage induced by laser-hematoporphyrin derivative
摘要
Abstract
Irradiation caused DNA single-strand breaks in S180 cells in the presence oflaser-hematoporphyrin derivative(HPD).The number of single strand breaks was 3.69 ×10~(10)break dolton~(-1).The analysis of base composition of DNA showed that the effect of laser-HPDirradiation on guanine was the highest,being 5-12 times as high as those of the three others(adenine,cytosine and thymine).It was different from the nature of DNA damage caused by γ-ray irradiation.
Enhua Cao, Fengying Chen, Shumin Xin. DNA damage induced by laser-hematoporphyrin derivative[J]. Chinese Journal of Lasers B, 1992, 1(4): 379. Enhua Cao, Fengying Chen, Shumin Xin. DNA damage induced by laser-hematoporphyrin derivative[J]. 中国激光(英文版), 1992, 1(4): 379.
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