光学学报, 2008, 28 (10): 1971, 网络出版: 2008-10-24
两种单光纤光镊捕获效果的数值仿真与实验研究
Numerical Simulation and Experiments of Two Fiber Optical Tweezers
医用光学与生物技术 单光纤光镊 时域有限差分 光学捕获 流体力学法 medical optics and biotechnology single-fiber optical tweezers finite difference time domain (FDTD) optical trapping hydrodynamics method
摘要
采用一种基于时域有限差分(FDTD)的数值算法,仿真计算了抛物线形和大锥角形两种新型单光纤光镊的出射光场,并在稳态场下通过对麦克斯韦应力张量积分求得介质球在两种光场中受到的光阱力,得到大锥角型光纤端产生的光阱力较大的结论; 讨论了不同介质球大小、折射率,光纤探针形状对光阱力的影响。在实验中这两种光纤探针都实现了对水中酵母菌细胞的捕获,且采用流体力学法对抛物线形和大锥角形二种新型单光纤光镊产生的光阱力进行了标定。结果表明:基于FDTD数值仿真方法计算受力与实验结果一致,并且这种计算光纤光镊产生的光阱力的方法简单,适用; 且抛物线形和大锥角形光纤探头都具备构成单光纤光镊的条件。
Abstract
The finite difference time domain (FDTD) method was used to calculate the output optical fields of parabolic and large angle single-fiber optical tweezers. The transverse and axial trapping forces were then obtained by integrating the Maxwell stress tensor in stable state. Compared with the parabolic fiber optical probe, the optical force of the large angle fiber probe is lager. Meanwhile, the influences of sizes and diffractive indexes of microscopic particles and profile of fiber probe on the optical force were considered. In experiment, these two fiber probes both successfully trap yeast cells in water and the two types of force are calibrated by hydromechanics. The results indicate that the optical force obtained by numerical simulation based on FDTD is in good agreement with that from experiments. This method is simple and suitable for the optical force calculation of fiber optical tweezers, and the parabolic and large angle optical fiber tips meet the demand of forming single-fiber optical tweezers.
吴忠福, 刘志海, 郭成凯, 杨军, 苑立波. 两种单光纤光镊捕获效果的数值仿真与实验研究[J]. 光学学报, 2008, 28(10): 1971. Wu Zhongfu, Liu Zhihai, Guo Chengkai, Yang Jun, Yuan Libo. Numerical Simulation and Experiments of Two Fiber Optical Tweezers[J]. Acta Optica Sinica, 2008, 28(10): 1971.