Chinese Optics Letters, 2008, 6 (12): 910, Published Online: Dec. 17, 2008  

Simultaneous imaging and measurement of tensile stress on cornea by using a common-path optical coherence tomography system with an external contact reference

Author Affiliations
1 Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign, 405 North Mathews Avenue, Urbana, Illinois 61801, USA
2 Department of Electrical and Computer Engineering, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, USA
Abstract
The objective of this study is to demonstrate that tensile stress resulting due to applied force on cornea can be accurately measured by using a time-domain common-path optical coherence tomography (OCT) system with an external contact reference. The unique design of the common-path OCT is utilized to set up an imaging system in which a chicken eye is placed adjacent to a glass plate serving as the external reference plane for the imaging system. As the force is applied to the chicken eye, it presses against the reference glass plate. The modified OCT image obtained is used to calculate the size of contact area, which is then used to derive the tensile stress on the cornea. The drop in signal levels upon contact of reference glass plate with the tissue are extremely sharp because of the sharp decline in reference power levels itself, thus providing us with an accurate measurement of contact area. The experimental results were in good agreement with the numerical predictions. The results of this study might be useful in providing new insights and ideas to improve the precision and safety of currently used ophthalmic surgical techniques. This research outlines a method which could be used to provide high resolution OCT images and a precise feedback of the forces applied to the cornea simultaneously.

Utkarsh Sharma, Jin U.. Simultaneous imaging and measurement of tensile stress on cornea by using a common-path optical coherence tomography system with an external contact reference[J]. Chinese Optics Letters, 2008, 6(12): 910.

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