光学 精密工程, 2008, 16 (7): 1285, 网络出版: 2010-02-28
在多层介质中的频域OCT蒙特卡罗仿真
Monte Carlo simulation of Fourier-domain OCT in multi-layered media
蒙特卡罗仿真 频域OCT 一阶Born近似 多层介质 Monte Carlo simulation Fourier Domain Optical Coherence Tomography(FDOCT) first-order Born approximation multi-layered media
摘要
选择多层介质作为样品,根据波恩一阶近似理论建立了单次散射的无限细直光束频域OCT模型,并分析了散射积分方程很难得到精确解的原因。蒙特卡罗仿真结果表明,一类和二类光子出射后在空间的分布存在着一定的差异,通过调整接收器的面积,可以在一定程度上很好地抑制二类光子,尽可能多地接收一类光子;通过分析时域OCT与频域OCT的区别,进一步确立了频域OCT的优势地位;通过改变复杂生物组织的模型结构,对由于能量衰减而造成的图像灰度失真做了近似的补偿。
Abstract
According to the theory of first-order Born approximation,a Fourier Domain Optical Coherence Tomography(FDOCT) model of single scattering infinite narrow beam is established,and the reason why it is hard to obtain the exact solution of integrated scattering equation is analyzed.The Monte Carlo simulation results indicate that two kinds of photon are different in spatial distributions.The multiple backscattering photons can be rejected and more single backscattering photons can be received by adjusting the detection area.Then,the advantage of FDOCT is confirmed by analyzing the differences between Time Domain OCT(TDOCT) and FDOCT.The simulation results provide an important reference for experiments.The gray level distortion of complex bio-tissue image resulting from energy attenuation can be approximately compensated by changing the model's structure.
李刚, 郑羽, 林凌, 刘晶晶. 在多层介质中的频域OCT蒙特卡罗仿真[J]. 光学 精密工程, 2008, 16(7): 1285. LI Gang, ZHENG Yu, LIN Ling, LIU Jing-jing. Monte Carlo simulation of Fourier-domain OCT in multi-layered media[J]. Optics and Precision Engineering, 2008, 16(7): 1285.