中国激光, 2010, 37 (6): 1421, 网络出版: 2010-07-07
基于空心光纤构建微管生物传感器的实验研究
Experimental Research on Micro-Tube Biosensor Based on Hollow Optical Fiber
传感器 生物传感器 空心光纤 回音壁谐振模 折射率 sensors biosensor hollow optical fiber whispering gallery mode refractive index
摘要
基于空心光纤构建微管生物传感器,进行了空心光纤的回音壁谐振模(WGM)理论分析,阐述了基于折射率变化检测的微管生物传感器工作原理。采用ZF13棱镜通过倏逝场耦合成功激发了微管的回音壁谐振模。利用不同浓度的乙醇水溶液初步展示了微管生物传感器回音壁谐振模谐振波长对折射率的敏感性,在1555.0 nm谐振波长处,当入射光角度为45°时,获得2.2 nm/RIU(RIU为折射率单元)的传感灵敏度,在入射光角度为36°时,获得21.2 nm/RIU的传感灵敏度。
Abstract
Micro-tube biosensor is established with hollow optical fiber and its whispering gallery mode (WGM) is analyzed theoretically. The principle of bio-sensing based on the change of refractive index is presented. With the prism of ZF13, WGM of micro-tube is successfully observed by evanescent coupling. The mixture of water and ethanol is used for experimental research on sensitivity with the change of refractive index of micro-tube biosensor. At the resonance wavelength of 1555.0 nm, 2.2 nm/RIU sensitivity is obtained with 45° incident angle and 21.2 nm/RIU is obtained with 36° incident angle.
江俊峰, 李海伟, 刘铁根, 刘琨, 张以谟. 基于空心光纤构建微管生物传感器的实验研究[J]. 中国激光, 2010, 37(6): 1421. Jiang Junfeng, Li Haiwei, Liu Tiegen, Liu Kun, Zhang Yimo. Experimental Research on Micro-Tube Biosensor Based on Hollow Optical Fiber[J]. Chinese Journal of Lasers, 2010, 37(6): 1421.