基于组织光学原理研发了组织氧饱和度无损检测仪。 利用该仪器检测了101名受试者(其中健康锻炼者42人, 健康不锻炼者34人, 脾虚证患者25人)在进行递增负荷功率自行车运动实验时, 股四头肌外侧头的肌氧变化过程。 测得的血红蛋白浓度(ｃtHb)受脂肪等外层组织影响较大, 而肌氧饱和度(rSO2)受影响较小。 实验结果显示, 在运动过程中, 随着运动负荷的逐渐增加, 骨骼肌中的总血红蛋白浓度逐渐上升, 肌氧饱和度逐渐降低； 当运动停止后, 总血红蛋白浓度和肌氧饱和度都出现快速上升。 运动中肌氧饱和度的变化幅度与受试者运动能力有密切关系。 利用局部组织氧饱和度这一指标来评价肌肉组织中氧的输送与消耗的平衡点, 进而实现了对肌肉组织有氧代谢能力的定量评估。

Based on the principles of organizational optics, the noninvasive tissue oxygenation saturation monitor was developed. The monitor was used to continuously monitor the changes in regional oxygen index of the thigh vastus lateralis in 101 volunteers, who performed an incremental intensity exercise on bicycle ergometer. Among the volunteers, 42 are athletes, 25 are patients whose spleens are asthenic, and the other 34 are controls. Hemoglobin concentration (ｃtHb) measured was heavily influenced by the thickness of fattiness; however, regional oxygen saturation (rSO2) was influenced much lightly. In the experiment, following increasing exercise intensity of the volunteers, their ｃtHb increased, while their rSO2 decreased. When the volunteers stopped the exercise, both of their ｃtHb and rSO2 increased quickly. The results showed that the regional saturation of oxygen of muscle was closely correlated with physical performance. The changes of regional saturation of oxygen of muscle can be used to evaluate the balance between supply and consumption of oxygen, and quantitatively assess the capability of oxidative metabolism in muscles.