利用微流体技术和双重乳液技术对大直径聚芳亚胺亚胺酮空心微球的制备条件进行了讨论。完成了微球壁厚和直径的控制研究, 并讨论了密度不匹配对微球质量的影响。获得了直径0.6～2 mm, 壁厚5～20.0 μm的聚合物微球材料, 并对微球制备过程中相分离对聚合物微球形貌的影响进行了分析, 结果表明：在聚合物微球外表面易于进行spinodal分相, 而在内表面易于进行binodal分相, 因此微球内外表面具有不同的形貌结构。同批次制备微球中, 平均直径±5%范围内的微球数占88%, 球形度大于99%。

Large diameter (0.6～2．０ mm) microshells of poly(imine imine ketone)s (PIIKs) were prepared by micro-liquid technique and double-layer latex technique. A double T-channel droplet generator was designed and developed for the fabrication of PIIKs microshells of controlled size continuously. Manipulative conditions of the diameter and thickness of shells were studied, and the effect of density mismatch on shell quality was discussed. Phase separation during the preparation process affects the morphology of shells. Spinodal phase separation tends to occur at the outer surface of the shells, while binodal phase separation at the inner surface. The diameters of PIIKs shells were measured, 88% of which vary in ±5% of the average diameter. The sphericity is better than 99%．