提出了一种利用六氯乙烷给取代芳烃引入氯原子的方法。将取代芳烃在低温下制成锂(钾)试剂, 再与六氯乙烷反应, 可以得到较高转化率的氯代芳烃。分别对邻位无氟原子取代基、单氟原子取代基、双氟原子取代基三类中间体进行了合成方法研究。通过元素分析、质谱等对产物结构进行了确认和表征。该方法具有反应收率高、产品纯度好、成本较低等特点。

A new synthetic method to introduce chlorine atoms in aromatic rings by using hexachloroethane is proposed in this paper. At low temperature, the lithium (potassium) reagent is made from substituted aromatics. Then, this reagent reacts with hexachloroethane to obtain chlorinated aromatic hydrocarbons with high conversion rate. In this way, the synthesis of three different intermediates, which are ortho-no-fluorine atoms substituted, one fluorine atom substituent, double fluorine atom substituent, are studied. The products are characterized by mass and element analysis. The advantages of this method are high yield, good purity and lower cost, etc.