Theoretically and experimentally, the effects of temperature on the weak principal axis of twisted optical fiber loop are analyzed, and the results show that the location of the pair of weak principal axis will drift with temperature change, which will deteriorate the stability of system when applied to sensor system. In this paper, the influence of phase drift of weak principal axis on the performance of optical fiber current sensor is mainly predicted theoretically. Our research results will provide a beneficial reference for improving optical fiber sensor system.