光谱学与光谱分析, 2011, 31 (8): 2127, 网络出版: 2011-08-29
拉曼技术应用于雌激素检测的研究
Study of Raman Technique Applied to Estrogen
17β-雌二醇(C18H24O2) 雌三醇(C18H24O3) 乙烯雌酚(C18H20O2) 拉曼光谱 表面增强 17β-Estradiol Estriol Diethylstilbestrol Raman spectroscopy SERS
摘要
应用RM-200型便携式拉曼光谱仪, 对17β-雌二醇(C18H24O2)、 雌三醇(C18H24O3)和乙烯雌酚(C18H20O2)三种激素类药品进行拉曼光谱检测。 并对三种雌激素进行了分析比对和模拟计算, 对其中较难检测的乙烯雌酚, 应用表面增强拉曼光谱技术获得了其拉曼光谱。 结果表明, 拉曼技术可以快速准确的定性检测出17β-雌二醇(C18H24O2)、 雌三醇(C18H24O3)和乙烯雌酚(C18H20O2)等雌激素。
Abstract
The authors acquired Raman spectra of three kinds of estrogen by portable Raman spectrometer, including 17β-estradiol (C18H24O2), estriol (C18H24O3) and diethylstilbestrol (C18H20O2). Analysis, comparison and simulation of the three estrogens were carried out, and the diethylstilbestrol Raman spectrum, which is hard to detect, was acquiredt by surface enhanced Raman scattering technology. Results show that Raman technique can detect 17β-estradiol (C18H24O2), estriol (C18H24O3) and diethylstilbestrol (C18H20O2) quickly and accurately.
冯超, 董鹍, 吴永军, 张鹏翔. 拉曼技术应用于雌激素检测的研究[J]. 光谱学与光谱分析, 2011, 31(8): 2127. FENG Chao, DONG Kun, WU Yong-jun, ZHANG Peng-xiang. Study of Raman Technique Applied to Estrogen[J]. Spectroscopy and Spectral Analysis, 2011, 31(8): 2127.
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