光子学报, 2009, 38 (10): 2598, 网络出版: 2011-11-17
光学相干层析术提取色散信息的初步研究
Dispersion Extraction with Optical Coherence Tomography: a Pilot Study
医用光学与生物技术 光学相干层析成像 色散提取 Fourier变换 二阶色散 Medical optics and biotechnology Optical coherence tomography Dispersion extraction Fourier transforms Second order dispersion
摘要
为了提取生物组织的色散信息，提出了一种基于Fourier变换以及多项式拟合的方法.该方法通过对光学相干层析术的干涉包络进行Fourier变换，再将得到的相位谱进行多项式拟合以实现色散信息的提取.通过数值模拟及相关实验验证了该方法的可行性.本文的分析结果不但有助于实现动态的色散补偿，而且可以用于区分不同的生物组织，以及同一生物组织的不同生理状态.
Abstract
The dispersion signal in optical coherence tomography (OCT) carries the information about the structure and function of bio-tissues.In order to extract the information about the dispersion,a method based on the Fourier transform and the polynomial fit was presented.The interferogram envelope in OCT was Fourier transformed to the frequency domain,and then the second order dispersion information was obtained by performing a polynomial fit to the phase spectrum.Theoretical simulation and experimental data validated the method.The obtained results in this work not only could be used for the dynamical dispersion compensation,but also provide a way to characterize different tissues,and different physiological conditions.
李鹏, 高万荣. 光学相干层析术提取色散信息的初步研究[J]. 光子学报, 2009, 38(10): 2598. Li Peng, Gao Wan-rong. Dispersion Extraction with Optical Coherence Tomography: a Pilot Study[J]. ACTA PHOTONICA SINICA, 2009, 38(10): 2598.
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