激光透射连接具有生物相容性的异种材料在生物医学植入体及其封装中具有良好的应用前景。利用半导体激光器对镀钛玻璃与聚对苯二甲酸乙二酯(PET)进行激光透射连接试验，其中玻璃上镀钛薄膜是通过射频磁控溅射方法完成的镀膜。通过单因素工艺研究了主要工艺参数激光功率、扫描速度和镀钛薄膜的厚度对连接强度的影响，并探讨了玻璃基片的表面粗糙度对镀钛薄膜粗糙度以及其连接强度的影响。通过搭接剪切试验得到镀钛玻璃与PET之间的连接强度，采用真彩共聚焦材料显微镜对拉伸失效后的试样表面进行观测和失效分析，使用X射线光电子能谱(XPS)检测激光透射连接过程中镀钛玻璃与PET之间化学键的形成信息。结果表明：主要工艺参数激光功率、扫描速度对连接强度有着重要影响，增加玻璃基片的粗糙度和镀钛薄膜的厚度可以提高其连接强度，为激光透射连接镀钛玻璃与聚合物提供了参考。

Transmission laser bonding of dissimilar and biocompatible materials has a potential application in biomedical implants and their encapsulation processes. PET and glass are bonded together by employing micro-scale titanium on glass using a near infrared continuous wave (CW) diode laser. Radio frequency magnetron sputtering deposition method is used to prepare Ti coating on glass substrates. The effect of main process parameters including laser power, scanning speed and film thickness of Ti coating on bond strength and bond width is investigated through the experiments based on single process parameters. The effect of surface roughness of glass substrate on the roughness of Ti coating and the bond strength is discussed. The bond strength between Ti coating glass and PET is obtained by lap-shear test. The information of failure analysis of laser bonded specimens after mechanical lap-shear test are gathered by true colour confocal microscopy for materials. The information of chemical bond for Ti coated glass and PET is collected from laser transmission bonding process by using X-ray photoelectron spectroscopy (XPS). Experimental results show that the main process parameters including laser power, scanning speed have a significant impact on bond strenghth, and the bond strength increases with the thickness of Ti coating and the surface roughness of glass substrates. Based on this research, it will be helpful for transmission laser bonding between Ti coated glass and polymer.