激光与光电子学进展, 2013, 50 (5): 051203, 网络出版: 2013-04-16
多功能时间分辨仪和苯丙酮尿症荧光仪一体化设计
Integrated Design of Multifunction TRFIA and Phenylketonuria Fluorometer
测量 医用光学 光学设计 一体化仪器设计 仪器检测 measurement medical optics optical design integrated instrument design testing of instrument
摘要
新生儿疾病筛查中需要使用荧光分析和时间分辨荧光免疫分析技术，而国内尚无集成两种测量手段的仪器。研发了一套可同时进行两种测量的透镜光纤结合型多功能时间分辨仪。根据美国临床实验室标准化委员会(NCCLS)文件以及相关文献，将研制的荧光仪和在国内各大医院已获广泛应用的标准仪器(雷勃仪器，THERMO Varioskan Flash全波长多功能酶标仪；芬兰PekinElmer Wallac1420多标记免疫分析仪)相比较，对所研发的仪器进行了全面评价。结果表明仪器的各项指标均符合要求，可考虑投入实际生产。
Abstract
Fluorescence analysis and time-resolved fluorescence immunoassay (TRFIA) are often used in screening of new born babies′ desease, while there is no domestic instrument having a collection of two measurements. A multi-function time-resolved instrument is developed to integrate two measurements, which is a lens-optical fiber combined instrument. According to the US. Committee for Clinical Laboratory Standards (NCCLS) documents and related literatures, the instrument is tested. It is compared with THERMO Varioskan Flash and PekinElmer Wallac 1420, which are used widely by major hospitals in China. The results show that the specification of the instrument are in line with requirements, and it could be put into practical production.
郭龙. 多功能时间分辨仪和苯丙酮尿症荧光仪一体化设计[J]. 激光与光电子学进展, 2013, 50(5): 051203. Guo Long. Integrated Design of Multifunction TRFIA and Phenylketonuria Fluorometer[J]. Laser & Optoelectronics Progress, 2013, 50(5): 051203.
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