激光与光电子学进展, 2013, 50 (10): 100606, 网络出版: 2013-09-04
用纳米光纤捕获和输送鸡血红细胞
Optical Trapping and Delivery of Chicken Red Blood Cells Using a Nanofiber
摘要
提出了用纳米光纤表面的倏逝波捕获和输送鸡血红细胞的方法。纳米光纤由通信用单模光纤通过热熔法拉制而成,直径为700 nm,光纤的一端直接与带有单模光纤输出端口的808 nm激光器相连接,插入损耗非常小。纳米光纤被完全浸入到鸡血红细胞的悬浮液中。通过实验观察发现,当导入纳米光纤中的激光功率增大到50 mW时,光纤附近的鸡血红细胞在倏逝波所产生的光梯度力的作用下,被捕获到光纤表面,并在光散射力的作用下,沿着光的传播方向运动,鸡血红细胞的运动速度约为2.9 μm/s。由进一步的实验分析可知,鸡血红细胞沿着光纤运动的平均速度与输入功率成线性拟合关系。利用该方法可以稳定地捕获和操控生物细胞和病毒等。
Abstract
A method is presented to trap and deliver chicken red blood cells by using evanescent wave around an optical nanofiber. The nanofiber is fabricated by drawing a standard telecommunication single mode optical fiber through a flame-heated treatment. The nanofiber has a diameter of 700 nm, with one end connected to an 808 nm laser source, leading to an extremely low insertion loss. The nanofiber is immersed in a solution of chicken red blood cells. The experimental result shows that, when the injected optical power is increased to 50 mW, the red blood cells near the nanofiber can be captured by optical gradient force and then delivered along the direction of light propagation due to the scattering force induced by the evanescent optical field. The calculated delivery velocity is 2.9 μm/s. By further experimental analysis, it is found that the velocity of red blood cells is linearly dependent on the input power. This technique could find some potential applications in trapping and manipulation of biological cells and virus.
李英, 胡艳军. 用纳米光纤捕获和输送鸡血红细胞[J]. 激光与光电子学进展, 2013, 50(10): 100606. Li Ying, Hu Yanjun. Optical Trapping and Delivery of Chicken Red Blood Cells Using a Nanofiber[J]. Laser & Optoelectronics Progress, 2013, 50(10): 100606.