光学学报, 2014, 34 (1): 0117001, 网络出版: 2013-12-25
样品散射对频域光学相干层析成像光谱形状和深度分辨率的影响
Effects of Scattering on Spectral Shape and Depth Resolution in Fourier Domain Optical Coherence Tomography
生物光学 光学成像 光学相干层析成像 散射 分辨率 biotechnology optical imaging optical coherence tomography scattering resolution
摘要
研究了样品散射性质对频域光学相干层析成像干涉谱信号和深度分辨率的影响。理论分析和模拟结果表明:样品散射使干涉谱信号的强度分布发生改变且向长波方向偏移,进而降低了成像的深度分辨率;样品的散射系数越大、深度越深,偏移越严重,深度分辨率降低越多;使用相应的校正函数可以提高深度分辨率。
Abstract
The effects of scattering on interference spectral signal and depth resolution in Fourier domain optical coherence tomography are researched. The results obtained from theoretical analysis and simulation show that scattering of sample can change the measured spectral shape, which shifts to longer wavelength, and decrease the depth resolution of image. When the value of scattering coefficient is larger and the position in sample is deeper, the spectral signal will shift more seriously and the depth resolution will decrease more. The depth resolution can be improved by using the corresponding correction function.
郭昕, 王向朝, 步鹏, 李中梁, 南楠, 黄炳杰. 样品散射对频域光学相干层析成像光谱形状和深度分辨率的影响[J]. 光学学报, 2014, 34(1): 0117001. Guo Xin, Wang Xiangzhao, Bu Peng, Li Zhongliang, Nan Nan, Huang Bingjie. Effects of Scattering on Spectral Shape and Depth Resolution in Fourier Domain Optical Coherence Tomography[J]. Acta Optica Sinica, 2014, 34(1): 0117001.