中国激光, 2013, 40 (s1): s104002, 网络出版: 2013-12-25
基于脉冲激光二极管辐射源的光声成像系统
Photoacoustic Imaging System Based on a Pulsed Laser Diode Excitation
生物光学 光声成像 脉冲激光二极管 三维图像重建 biotechnology photoacoustic imaging pulsed laser diode 3D image reconstruction
摘要
采用具有价格低、体积小、结构紧凑、重复率高等优点的脉冲激光二极管,搭建了一套C扫描模式的光声成像系统,并采用三维可视化光声重建技术,获得了被测样品的二维和三维光声影像。实验中,系统采用前向模式接收光声信号,激光二极管和超声探测器保持相对位置不变。实验结果表明,该成像系统横向分辨率为0.5 mm,光声信噪比可达20.6 dB,A扫描速度为0.16 s/div。该激光二极管的单脉冲能量低至14 μJ,整体体积只有10 cm×3 cm×3 cm,有望发展成为一种低成本、实时、便携式的生物组织无损光声成像系统。
Abstract
A C-scanning photoacoustic imaging system is designed with a pulsed laser diode, which has the properties of low cost, small size, compact structure, and high repetition frequency. The 3D-visual reconstruction algorithm is employed to observe the 2D and 3D photoacoustic image. During the experiments, the laser diode and the ultrasonic transducer keep the fixed positions using a front side detection configuration. The experimental results show that lateral resolution of the imaging system is determined as 0.5 mm, and the speed of A-scanning is 0.16 s/div with a signal-to-noise ratio of 20.6 dB. The laser diode is only 10 cm×3 cm×3 cm with a pulse energy output as low as 14 μJ. The proposal method has the potential to be developed as a configuration of inexpensive, real-time, and portable noninvasive photoacoustic imaging system for biomedical tissue.
曾吕明, 刘国栋, 杨迪武, 纪轩荣. 基于脉冲激光二极管辐射源的光声成像系统[J]. 中国激光, 2013, 40(s1): s104002. Zeng Lüming, Liu Guodong, Yang Diwu, Ji Xuanrong. Photoacoustic Imaging System Based on a Pulsed Laser Diode Excitation[J]. Chinese Journal of Lasers, 2013, 40(s1): s104002.