中国激光, 2014, 41 (2): 0204001, 网络出版: 2014-02-27
正弦相位调制全深度频域多普勒光学相干层析成像技术
Full-Range Fourier Domain Doppler Optical Coherence Tomography Based on Sinusoidal Phase Modulation
医用光学 医疗与生物成像 光学相干层析 正弦相位调制 多普勒探测 medical optics medical and biological imaging optical coherence tomography sinusoidal phase modulation Doppler detection
摘要
将多普勒探测与正弦相位调制复频域光学相干层析成像技术(OCT)相结合，建立了基于正弦相位调制的全深度频域多普勒光学相干层析成像系统。利用正弦相位调制B-M扫描方法，并采用傅里叶变换结合带通滤波的方法重建复干涉谱信号，获得全深度层析及多普勒图像。成像深度范围扩大为原来的2倍，在整幅图像范围内均可获得较高的速度探测灵敏度。基于该系统获得了血流仿体的全深度层析图及全深度多普勒图。实验测量的系统最小可探测速度为5.35 μm/s。
Abstract
A full-range Fourier domain Doppler optical coherence tomography (DOCT) system based on sinusoidal phase-modulating method is developed. The system combines Doppler detection with complex Fourier domain OCT. Full-range OCT and Doppler images are achieved using the complex spectral interferogram, which is retrieved based on the sinusoidal phase modulation B-M scanning and the combination of Fourier transform analysis and bandpass filter method. With the system, the depth imaging range is doubled and high velocity sensitivity is available in the whole B-scan image. Full-range OCT and full-range Doppler images of a flow phantom are achieved with the proposed system. The minimum detectable velocity of the system is investigated, which is 5.35 μm/s.
南楠, 步鹏, 李中梁, 郭昕, 王向朝. 正弦相位调制全深度频域多普勒光学相干层析成像技术[J]. 中国激光, 2014, 41(2): 0204001. Nan Nan, Bu Peng, Li Zhongliang, Guo Xin, Wang Xiangzhao. Full-Range Fourier Domain Doppler Optical Coherence Tomography Based on Sinusoidal Phase Modulation[J]. Chinese Journal of Lasers, 2014, 41(2): 0204001.
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