Chinese Optics Letters, 2014, 12 (s2): S23002, Published Online: Sep. 11, 2014  

SERS measurement of cancerous cells with optical fiber sensor Download: 673次

Author Affiliations
1 Key Laboratory of Specialty Fiber Optics and Optical Access Networks, Shanghai University, Shanghai 200072, China
2 Laboratory for Microstructures, Shanghai University, Shanghai 00444, China
Abstract
The optical fiber nanoprobe is prepared using spark fused taper and acid corrosion methods. With 3-ami-nopropyltrimethoxysilane coupling, gold nanoparticles are solidified onto the surface of fiber optic and then the optical fiber sensor is prepared using the surface-enhanced Raman spectroscopy (SERS) measurement of the cell solution. The SERS of the esophageal cancer cell solution is measured by direct detection and fiber detection methods. Similar results are obtained by both detection methods. SERS measurement of tissues and organs is done using the optical fiber sensor.

Shupeng Liu, Yuxue Bai, Zhenyi Chen, Na Chen, Jing Huang, Lianxin Li, Bo Lu. SERS measurement of cancerous cells with optical fiber sensor[J]. Chinese Optics Letters, 2014, 12(s2): S23002.

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