流动注射-氢化物发生-原子荧光光谱法由于具有灵敏度高、 测量范围宽、 分析速度快等很多优点, 在卫生、 环保、 地质、 冶金等行业得到了广泛应用。 但是, 影响氢化物发生-原子荧光光谱仪灵敏度和谱峰展宽的因素很多, 一般都是通过多次实验寻找最佳实验条件, 实验条件的优化比较困难。 针对这一问题, 根据氢化物发生化学反应的特点以及检测系统的组成原理, 利用质量守恒等物理定律, 提出了一个测试系统的数学模型, 建立了各实验参数与仪器灵敏度和谱峰展宽系数之间的函数关系, 以对-氨基苯胂酸标准品的测试为例, 通过理论仿真与实验结果相比较, 证明这个模型能很好的模拟实验系统。 最后, 利用提出的数学模型, 本文给出了各参数与灵敏度和谱峰展宽的关系图, 提出气液分离器的容积、 载流流速和进样体积是影响系统灵敏度和谱峰展宽的主要因素, 利用这个关系图, 综合调整三个参数, 可以使灵敏度提高到原来的2.9倍, 谱峰展宽缩小到原来的0.76, 为优化实验条件提供了理论指导。

Flow injection-hydride generation-atomic fluorescence spectrometry was a widely used method in the industries of health, environmental, geological and metallurgical fields for the merit of high sensitivity, wide measurement range and fast analytical speed. However, optimization of this method was too difficult as there exist so many parameters affecting the sensitivity and broadening. Generally, the optimal conditions were sought through several experiments. The present paper proposed a mathematical model between the parameters and sensitivity/broadening coefficients using the law of conservation of mass according to the characteristics of hydride chemical reaction and the composition of the system, which was proved to be accurate as comparing the theoretical simulation and experimental results through the test of arsanilic acid standard solution. Finally, this paper has put a relation map between the parameters and sensitivity/broadening coefficients, and summarized that GLS volume, carrier solution flow rate and sample loop volume were the most factors affecting sensitivity and broadening coefficients. Optimizing these three factors with this relation map, the relative sensitivity was advanced by 2.9 times and relative broadening was reduced by 0.76 times. This model can provide a theoretical guidance for the optimization of the experimental conditions.