红外, 2015, 36 (4): 43, 网络出版: 2015-05-20
太赫兹波对肠黏液的光谱检测
Detection of Human Intestinal Mucus by Terahertz Pulsed Spectroscopy
太赫兹时域光谱技术 肠癌 肠黏液 频谱分析 吸收系数 折射率指数 terahertz time-domain spectroscopy colon cancer intestinal mucus spectroscopic analysis absorption coefficient refractive index
摘要
主要利用太赫兹时域光谱技术对人体正常肠组织表面黏液与癌变肠组织表面黏液进行检测。分别获得了不同样品在0.2 THz~0.8 THz波段的吸收系数和折射率。研究发现,新鲜正常肠组织表面黏液的太赫兹吸收与水的吸收接近,这提示水的贡献是主要的。同时,癌变肠组织表面黏液在吸收系数和折射率强度上普遍比正常肠组织表面黏液样品高,这表明该技术在癌组织检测中具有潜在的应用。研究结果表明,太赫兹时域光谱技术在生物组织检测和临床医学如肿瘤疾病诊断方面具有广泛的应用前景。
Abstract
The different surface mucus from human normal and cancerous intestinal tissues were investigated by terahertz time-domain spectroscopy technique and the absorption coefficient and refractive index were obtained in the range from 0.2to 0.8 THz. The study found that the terahertz absorption intensity of fresh normal mucus is close to water, which indicating that the water in fresh tissue occupies the main contribution. The cancerous samples showed higher absorption coefficient and refractive index than that of the normal samples. It suggests that terahertz spectroscopy possesses the capability of identifying the cancerous tissue which has great potential application prospect in biological detection and tumor disease diagnosis.
单翌, 赵红卫, 刘勇超, 黄广建, 朱亦鸣. 太赫兹波对肠黏液的光谱检测[J]. 红外, 2015, 36(4): 43. SHAN Yi, ZHAO Hong-wei, LIU Yong-chao, HUANG Guang-jian, ZHU Yi-ming. Detection of Human Intestinal Mucus by Terahertz Pulsed Spectroscopy[J]. INFRARED, 2015, 36(4): 43.