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OCT内窥镜的研究现状与展望

Research Status and Prospect of Endoscopic OCT

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摘要

光学相干断层(OCT)内窥镜是OCT 与医用电子内窥镜相结合的新型光学成像技术。随着OCT 的迅猛发展,基于OCT 的内窥镜技术由于具有微米级分辨率和无损实时成像的优势逐渐成为研究热点。主要介绍了OCT 技术的基本原理、种类以及包括探测深度、纵向分辨率和横向分辨率在内的重要参数;简述了OCT 内窥镜扫描探头的发展进程和研究成果,从探头外径、扫描速度、横向分辨率和纵向分辨率方面,对不同OCT 内窥镜扫描探头进行了比较;总结了OCT 内窥镜侧向扫描探头在胃肠道、支气管、血管等器官诊断方面和前向扫描探头在卵巢、乳腺、脑等器官诊断方面的应用。

Abstract

Optical coherence tomography (OCT) endoscope is a new optical imaging technology, which combines OCT with the medical electronic endoscope. With the rapid development of OCT, the endoscopic technology based on OCT becomes a popular research area for its micron level resolution and non-destructive real-time imaging. The basic principles and classification of OCT technology as well as several important parameters of OCT technology including the probing depth, axial resolution and lateral resolution are mainly introduced. Some recent research achievements and development of endoscopic OCT scanning probes are discussed, and the endoscopic OCT scanning probes are compared in terms of outer diameter, scanning speed, axial resolution and lateral resolution. The applications of side-imaging OCT probes in gastrointestinal tract, respiratory tract, blood vessels and other organs as well as the applications of forward-imaging OCT probes in ovaries, breast, brain and other organs are summarized.

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中图分类号:O439

DOI:10.3788/lop52.100006

所属栏目:综述

基金项目:国家自然科学基金(81271568)、教育部博士点基金(20111101120028)

收稿日期:2015-04-20

修改稿日期:2015-05-18

网络出版日期:2015-09-23

作者单位    点击查看

刘景宇:北京理工大学生命学院, 北京 100081
张春雨:北京理工大学生命学院, 北京 100081
唐晓英:北京理工大学生命学院, 北京 100081
高天欣:北京理工大学生命学院, 北京 100081

联系人作者:刘景宇(158556963@qq.com)

备注:刘景宇(1990—),男,硕士研究生,主要从事光学相干断层扫描方面的研究。

【1】Davis C J, Filpi C J. A history of endoscopic surgery[J]. Principles of Laparoscopic Surgery, 1992, 2(1): 16-23.

【2】Huang D, Swanson E A, Lin C P, et al.. Optical coherence tomography[J]. Science, 1991, 254(5035): 1178-1181.

【3】Sergeev A M, Gelikoniv V M, Gelikonov G V, et al.. In vivo endoscopic OCT imaging of precancer and cancer states of human mucosa[J]. Optics Express, 1997, 1(13): 432-440.

【4】Liang S, Saidi A, Jing J, et al.. Intravascular atherosclerotic imaging with combined fluorescence and optical coherence tomography probe based on a double-clad fiber combiner[J]. Journal Of Biomedical Optics, 2012, 17(7): 070501.

【5】Yazdanfar S, Rollins A M, Izatt J A. Imaging and velocimetry of the human retinal circulation with color Doppler optical coherence tomography[J]. Optics Letters, 2000, 25(19): 1448-1450.

【6】Morgner U, Drexler W, Kartner F X, et al.. Spectroscopic optical coherence tomography[J]. Optics Letters, 2000, 25(2): 111-113.

【7】de Boer J F, Milner T E, Nelson J S, et al.. Two-dimensional birefringence imaging in biological tissue by polarizationsensitive optical coherence tomography[J]. Optics Letters, 1997, 22(12): 934-936.

【8】Yu Daoyin, Chen Xiaodong, Wang Yi, et al.. Medical ultrasound-research of imaging system endoscopic OCT[J]. Science China, 2007, 37(1): 75-79.
郁道银, 陈晓冬, 汪毅, 等. 医学超声-OCT 内窥成像系统的研究[J]. 中国科学, 2007, 37(1): 75-79.

【9】Wojtkowski M, Leitgeb R, Kowalczyk A, et al.. In vivo human retinal imaging by Fourier domain optical coherence tomography[J]. Journal of Biomedical Optics, 2002, 7(3): 457-463.

【10】Tearney G J, Boppart S A, Bouma B E, et al.. Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography[J]. Optics Letters, 1996, 21(12): 543-545.

【11】Bouma B E, Tearney G J. Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography[J]. Optics Letters, 1999, 24(8): 531-533.

【12】Tran P H, Mukai D S, Brenner M, et al.. In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe[J]. Optics Letters, 2004, 29(11): 1236-1238.

【13】Kim K H, Park B H, Maguluri G N, et al.. Two-axis magnetically-driven MEMS scanning catheter for endoscopic highspeed optical coherence tomography[J]. Optics Express, 2007, 15(26): 18130-18140.

【14】Wu Y, Xi J, Huo L, et al.. Robust high-resolution fine OCT needle for side-viewing interstitial tissue imaging[J]. IEEE Journal of Selected Topics in Quantum Electronics, 2010, 16(4): 863-869.

【15】Lorenser D, Yang X, Kirk R W, et al.. Ultrathin side-viewing needle probe for optical coherence tomography[J]. Optics Letters, 2011, 36(19): 3894-3896.

【16】Wang D, Fu L, Wang X, et al.. Endoscopic swept-source optical coherence tomography based on a two-axis microelectromechanical system mirror[J]. Journal of Biomedical Optics, 2013, 18(8): 086005.

【17】Boppart S A, Bouma B E, Pitris C, et al.. Forward-imaging instruments for optical coherence tomography[J]. Optics Letters, 1997, 22(11): 1618-1620.

【18】Sergeev A M, Gelikoniv V M, Gelikonov G V, et al.. In vivo endoscopic OCT imaging of precancer and cancer states of human mucosa[J]. Optics Express, 1997, 1(13): 432-440.

【19】Pan Y T, Xie H K, Fedder G K. Endoscopic optical coherence tomography based on a microelectromechanical mirror [J]. Optics Letters, 2001, 26(24): 1966-1968.

【20】Xie T Q, Xie H K, Fedder G K, et al.. Endoscopic optical coherence tomography with a modified microelectromechanical systems mirror for detection of bladder cancers[J]. Applied Optics, 2003, 42(31): 6422-6426.

【21】Han S, Sarunic M V, Wu J, et al.. Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection[J]. Journal of Biomedical Optics, 2008, 13(2): 020505.

【22】Park H, Song C, Kang M, et al.. Forward imaging OCT endoscopic catheterbased on MEMS lens scanning[J]. Optics Letters, 2012, 37(13): 2673-2675.

【23】Joos K, Shen J. Miniature real-time intraoperative forward-imaging optical coherence tomography probe[J]. Biomedical Optics Express, 2013, 4(1342): 1342-1350.

【24】Sergeev A M, Gelikonov V M, Gelikonov G, et al.. In vivo optical coherence tomography of human skin microstructure [J]. Society of Photo-Optical Instrumentation Engineers, 1994, 2328: 144-150.

【25】Colston B W, DaSilva L B, Everett M J, et al.. Dental OCT[J]. Optics Express, 1998, 3(6): 230-238.

【26】Tearney G J, Brezinski M E, Bouma B E, et al.. In vivo endoscopic optical biopsy with optical coherence tomography [J]. Science, 1997, 276(5321): 2037-2039.

【27】Qi X, Pan Y, Sivak M V, et al.. Image analysis for classification of dysplasia in Barrett′ s esophagus using endoscopic optical coherence tomography[J]. Biomedical Optics Express, 2010, 1(3): 825-847.

【28】Li X, Boppart S, Van D, et al.. Optical coherence tomography: Advanced technology for the endoscopic imaging of Barrett''s esophagus[J]. Endoscopy, 2000, 32(12): 921-930.

【29】Tsai T, Zhou C, Tao Y, et al.. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett′s esophagus radiofrequency ablation treatment response [J]. Gastrointestinal Endoscopy, 2012, 76(6): 1104-1112.

【30】Testoni P A, Mangiavillano B. Optical coherence tomography in detection of dysplasia and cancer of the gastrointestinal tract and bilio-pancreatic ductal system[J]. World Journal of Gastroenterology, 2008, 14(42): 6444-6452.

【31】Shen B, Jr G Z, Gramlich T L, et al.. In vivo colonoscopic optical coherence tomography for transmural inflammation in inflammatory bowel disease[J]. Clinical Gastroenterology and Hepatology, 2004, 2(12): 1080-1087.

【32】Pitris C, Brezinski M E, Bouma B E, et al.. High resolution imaging of the upper respiratory tract with optical coherence tomography-A feasibility study[J]. American Journal of Respiratory and Critical Care Medicine, 1998, 157(5): 1640-1644.

【33】Tsuboi M, Hayashi A, Ikeda N, et al.. Optical coherence tomography in the diagnosis of bronchial lesions[J]. Lung Cancer, 2005, 49(3): 387-394.

【34】Brezinski M E, Tearney G J, weissman N J, et al.. Assessing atherosclerotic plaque morphology: Comparison of optical coherence tomography and high frequency intravascular ultrasound[J]. Heart, 1997, 77(5): 397-403.

【35】Bonnema G T, Cardinal K O, McNally J B, et al.. Assessment of blood vessel mimics with optical coherence tomography [J]. Journal of Biomedical Optics, 2007, 12(2): 024018.

【36】Boppart S A, Goodman A, Libus J, et al.. Imaging of endometriosis and ovarian carcinoma with optical coherence tomography: Feasibility for laparoscopic-based imaging[J]. British Journal of Obstetrics and Gynaecology, 1999, 106(10): 1071-1077.

【37】Hariri L P, Bonnema G T, Schmidt K, et al.. Laparoscopic optical coherence tomography imaging of human ovarian cancer[J]. Gynecologic Oncology, 2009, 114(2): 188-194.

【38】Boppart S A, Luo W, Marks D L, et al.. Optical coherence tomography: Feasibility for basic research and image-guided surgery of breast cancer[J]. Breast Cancer Research and Treatment, 2004, 84(2): 85-97.

【39】Liang C, Wierwille J, Moreira T, et al.. A forward-imaging needle-type OCT probe for image guided stereotactic procedures[J]. Optics Express, 2011, 19(27): 26283-26294.

引用该论文

Liu Jingyu,Zhang Chunyu,Tang Xiaoying,Gao Tianxin. Research Status and Prospect of Endoscopic OCT[J]. Laser & Optoelectronics Progress, 2015, 52(10): 100006

刘景宇,张春雨,唐晓英,高天欣. OCT内窥镜的研究现状与展望[J]. 激光与光电子学进展, 2015, 52(10): 100006

被引情况

【1】陈俊波,曾亚光,袁治灵,唐志列. 基于动态散斑的光学相干层析成像技术. 光学学报, 2018, 38(1): 111001--1

【2】张晨曦,陈明惠,王帆,高乃珺,郑刚. 小波变换和分数阶积分结合的OCT图像去噪算法. 激光与光电子学进展, 2019, 56(18): 181008--1

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