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拉曼光谱在胃癌诊断中的应用与研究进展

Application and Research Progress of Raman Spectroscopy Diagnosis in the Gastric Cancer

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摘要

拉曼光谱是一种分子振动光谱技术, 具有分子水平的肿瘤检测和诊断能力。胃癌是常见恶性肿瘤, 经常到晚期才得到诊断, 死亡率较高, 而早期胃癌预后较好, 因此胃癌早期检测和诊断显得尤为重要。文章介绍了拉曼光谱用于胃癌早期检测和诊断的应用, 并综述其研究进展, 结果认为拉曼光谱探针与内镜整合, 将实现胃癌活体检测和诊断, 极具临床应用价值。

Abstract

Raman spectroscopy is a molecular vibrational spectroscopic technique that is capable of optically probing the biomolecular changes associated with diseased transformation. Gastric cancer is currently the fourth most common malignancy, and also the second leading cause of cancer deaths in humans worldwide. As the possibilities in the treatment of gastric cancer continue to evolve, its early detection and correct diagnosis are becoming increasingly important. The paper presents an overview of the in vitro and in vivo work on the application of Raman spectroscopy and discusses its potential as a new tool in the clinic implementation.

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中图分类号:O653

DOI:10.3969/j.issn.1007-7146.2011.02.025

所属栏目:专题综述

基金项目:武汉市科技攻关项目(200860423223)

收稿日期:2010-07-27

修改稿日期:2010-11-05

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作者单位    点击查看

易伟松:武汉大学化学与分子科学学院, 湖北 武汉 430072华中农业大学理学院, 湖北 武汉 430070
江厚敏:武汉市黄陂区人民医院, 湖北 武汉 430030

联系人作者:易伟松(weisong_yi@mail.hzau.edu.cn)

备注:易伟松(1977-), 男, 博士生, 主要从事生物医学拉曼光谱研究。

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引用该论文

YI Wei-song,JIANG Hou-min. Application and Research Progress of Raman Spectroscopy Diagnosis in the Gastric Cancer[J]. Acta Laser Biology Sinica, 2011, 20(2): 280-284

易伟松,江厚敏. 拉曼光谱在胃癌诊断中的应用与研究进展[J]. 激光生物学报, 2011, 20(2): 280-284

被引情况

【1】黄祖芳,曹 刚,孙 艳,杜生荣,李永增,林居强,冯尚源,雷晋萍. 拉曼光谱技术研究男性生殖生育. 光谱学与光谱分析, 2016, 36(9): 2818-2822

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