Chinese Optics Letters, 2016, 14 (3): 031701, Published Online: Aug. 6, 2018
Developing a contact probe for rodent fundus imaging in a confocal scanning laser ophthalmoscope Download: 890次
170.0170 Medical optics and biotechnology 170.4460 Ophthalmic optics and devices 170.5755 Retina scanning 170.2520 Fluorescence microscopy
Abstract
Since significant ocular differences in both anatomical structure and optical properties exist between rodents and humans, clinical imaging devices for human use are not suitable for use on rodents. In this study, we develop a contact probe with a flexible surface that can closely fit the rodent cornea for fundus imaging with a confocal scanning laser ophthalmoscope. Both Zemax simulation and in vivo fundus imaging demonstrate that this contact probe can significantly improve both the imaging quality and the operational convenience.
Xiaoyun Jiang, Yichen Ding, Wenyao Wang, Zhiyu Huang, Zhiru Wang, Elie de Lestrange Anginieur, Yue Yu, Jun Li, Mingliang Pu, Qiushi Ren, Changhui Li. Developing a contact probe for rodent fundus imaging in a confocal scanning laser ophthalmoscope[J]. Chinese Optics Letters, 2016, 14(3): 031701.