介绍了国外从原子到产品(A2P)研究，阐述了强约束集成微系统技术的微观架构及其两“微”内涵。在此基础上，将A2P 与强约束集成微系统理念相结合，提出了原子制造和原子微系统概念，并初步分析了其科学技术框架体系。我们认为，原子制造和原子微系统技术是从“材料到系统”的集成微系统技术向原子层次的进一步延伸和发展，主要包含如下内涵：a) 研究如何开发先进工艺，跨越原子尺度到宏观尺度的制造鸿沟，使得从原子出发集成定制的宏观尺度产品或系统能够保持优良的“原子级”特性；b) 研究原子层级微观特性在向宏观产品传递过程中的变化的物理过程，讨论如何实现原子层次优良特性的选择性保留以及新特性开发，进而实现系统更强功能及更高性能。原子制造和原子微系统技术具有很强的前沿性、颠覆性，有望为后摩尔定律时代提供一条全新的技术途径，引发一场新的重大技术革命。

Researches about Atoms to Product(A2P) are firstly introduced. Then the connotation of Strongly Constrained Integrated Microsystem(SCIMS) and its micro architecture are demonstrated. A new concept named atom assembly and atom microsystem is proposed based on these ideals, by blending the technological ideas of A2P and SCIMS. Its science & technology framework are analyzed preliminarily. It is believed that, atom assembly and atom microsystem is a further development and expansion deep into atom scale of SCIMS. It contains following principles and goals: first, to develop the technologies and processes to assemble nanoscale(atom scale) constituents into materials, components and systems that preserve distinctive nanoscale properties; second, to study the vanishing physical process of nanoscale properties when nanoscale constituents are manufactured at larger “product-scale” dimensions, and to exploit unique nanoscale characteristics which may benefit for “product-scale” systems with higher performance. The concept of atom assembly and atom microsystem is very frontier, challenging and subversive, which may provide a feasible approach for post Moore’s Law era and trigger a technological revolution.