中国激光, 2018, 45 (2): 0207013, 网络出版: 2018-02-28
基于稀土上转换发光纳米平台的光动力抗菌疗法的研究进展 
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Research Progress on Photodynamic Antimicrobial Chemotherapy Based on Rare Earth Upconversion Nanoplatform
医用光学 光动力抗菌疗法 稀土上转换纳米颗粒 协同治疗 多重耐药菌 medical optics photodynamic antimicrobial chemotherapy rare earth upconversion nanoparticles combination therapy multidrug-resistant bacteria
摘要
稀土上转换发光纳米颗粒（UCNPs）可将近红外光转化为紫外可见光，能有效解决光动力抗菌疗法（PACT）中组织穿透深度小、治疗效率低的问题。综述了基于稀土上转换发光纳米平台的光动力抗菌疗法的研究进展，并对新型联合抗菌平台的开发及其在临床上的应用进行了展望。
Abstract
Rare earth upconversion nanoparticles (UCNPs) can transform near-infrared light into ultraviolet-visible light, which can effectively solve the problems such as a low tissue penetration depth and a low treatment efficiency of photodynamic antimicrobial chemotherapy (PACT). The research progress on the photodynamic antimicrobial chemotherapy based on rare earth upconversion nanoplatforms is reviewed. The development of novel co-antibacterial platform and its clinical applications are prospected.
赵一铭, 刘成程, 王晶, 胡敏. 基于稀土上转换发光纳米平台的光动力抗菌疗法的研究进展[J]. 中国激光, 2018, 45(2): 0207013. Zhao Yiming, Liu Chengcheng, Wang Jing, Hu Min. Research Progress on Photodynamic Antimicrobial Chemotherapy Based on Rare Earth Upconversion Nanoplatform[J]. Chinese Journal of Lasers, 2018, 45(2): 0207013.
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