Graphene and other extraordinary two-dimensional materials together with recent advances in optical modulators have set the foundations for the widespread applications of next-generation optoelectronic devices. In this work, we report on the high-performance fundamentally mode-locked waveguide laser modulated by chemical-vapor-deposition-grown WSe₂ as a saturable absorber. By incorporating a WSe₂ sample into a monolithic Nd:YVO₄ waveguide platform, 6.526 GHz picosecond pulsed laser generation has been achieved at the wavelength of 1 μm with pulse duration of 47 ps.