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Photoacoustic effect invokes auditory response in infrared neuron stimulation

Photoacoustic effect invokes auditory response in infrared neuron stimulation

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Abstract

Accepted 25 September 2018 Published 6 December 2018 Infrared neuron stimulation is regarded as an innovative approach for stimulating cochleae in animals while the exact mechanism still remains unknown. In this paper, we studied compound action potentials of guinea pig cochleae with chronic or acute deafness. We recorded optical compound action potentials and analyzed stretched cochlear preparations by fluorescence microscopy. Photoacoustic signals were measured by hydrophone and microphone, respectively. In our experiment, we observed a switch response effect in vitro and in vivo experiments. Therefore, we proposed photoacoustic effect could invoke auditory response in infrared neuron stimulation.

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DOI:10.1142/s1793545818500402

基金项目:This projectwas supported by grants fromtheNature Science Foundation of China (Nos. NSFC81401539 andNSFC31271056) and the projects in the Shenzhen Medical Engineering Laboratory For Human Auditory-equilibrium Function.

收稿日期:2018-05-15

修改稿日期:2018-09-25

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Muqun Yang:Tsinghua-Berkeley Shenzhen Institute, Tsinghua University Nanshan Shenzhen 518071, P. R. China
Tian Guan:Graduate School at Shenzhen, Tsinghua University Nanshan Shenzhen 518055, P. R. China
Yonghong He:Graduate School at Shenzhen, Tsinghua University Nanshan Shenzhen 518055, P. R. China

联系人作者:Yonghong He(heyh@sz.tsinghua.edu.cn)

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引用该论文

Muqun Yang,Tian Guan,Yonghong He. Photoacoustic effect invokes auditory response in infrared neuron stimulation[J]. Journal of Innovative Optical Health Sciences, 2019, 12(1): 1850040

Muqun Yang,Tian Guan,Yonghong He. Photoacoustic effect invokes auditory response in infrared neuron stimulation[J]. Journal of Innovative Optical Health Sciences, 2019, 12(1): 1850040

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