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光声成像技术在早期癌症检测治疗中的潜在应用

Potential Applications of Photoacoustic Imaging in Early Cancer Diagnosis and Treatment

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摘要

光声成像技术通过检测光声效应中的超声信号,克服了光在生物组织体传输过程中的强散射作用,突破了传统光学成像的成像深度浅以及声学成像的对比度低的局限,在早期癌症检测中具有广泛的应用前景,有望成为肿瘤的诊断、定位、分期和治疗的有效手段。主要阐述了光声成像技术原理及其在早期癌症检测和治疗中的国内外临床应用研究现状,展望了光声成像技术在生物医学的应用潜力,分析了其未来的发展趋势和局限性。

Abstract

Photoacoustic imaging technique overcomes the strong scattering effects of light when transmitting in organisms by detecting the ultrasonic signals based on the photoacoustic effect, which avoids the limitations of low depth of traditional optical imaging and low contrast of acoustic imaging. This technique has potential applications in early cancer diagnosis and it can possibly become an effective method for tumor diagnosis, locating, staging and treating. The principle of photoacoustic imaging and the research status of its clinical applications in early cancer diagnosis and treatment at home and abroad are mainly described. The potential application of photoacoustic imaging technique in biological medicine is prospected, and its future development trend and limitations are also analyzed.

Newport宣传-MKS新实验室计划
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中图分类号:O463

DOI:10.3788/lop56.070001

所属栏目:综述

基金项目:国家自然科学基金(61675043,81571726)、福建省自然科学基金(2018J01785)

收稿日期:2018-09-05

修改稿日期:2018-10-05

网络出版日期:2018-10-22

作者单位    点击查看

吴华钦:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007
王昊宇:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007
谢文明:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007
李志芳:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007
吴淑莲:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007
李晖:福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室暨福建省光子技术重点实验室, 福建 福州 350007

联系人作者:李晖(hli@fjnu.edu.cn)

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引用该论文

Wu Huaqin,Wang Haoyu,Xie Wenming,Li Zhifang,Wu Shulian,Li Hui. Potential Applications of Photoacoustic Imaging in Early Cancer Diagnosis and Treatment[J]. Laser & Optoelectronics Progress, 2019, 56(7): 070001

吴华钦,王昊宇,谢文明,李志芳,吴淑莲,李晖. 光声成像技术在早期癌症检测治疗中的潜在应用[J]. 激光与光电子学进展, 2019, 56(7): 070001

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