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基于有限元仿真定量探究贵金属纳米探针自组装诱导的非线性光声效应增强机制

A Quantitative Study of the Nonlinear Enhancement of Photoacoustic Effect by Self-assembled Metal Nanoprobes Based on Finite Element Simulation

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摘要

构建高转化效率的功能纳米探针是推动光声分子成像发展的关键。随着光声分子成像技术的发展, 具有非线性增强光声转换效率的自组装纳米探针逐渐成为研究热点, 然而有关其非线性增强的定量研究尚未见报道。本文以纳米金球为例, 利用有限元仿真定量探究金属纳米探针自组装诱导的非线性光热及光声效应, 揭示自组装纳米探针光声效应增强规律, 为构建具备高转换效率的光声自组装纳米探针奠定了理论基础。

Abstract

Constructing functional nanoprobes with high conversion efficiency is the key to promote the development of photoacoustic molecular imaging. With the development of photoacoustic molecular imaging, self-assembled nanoprobes with nonlinear enhancement of photoacoustic conversion efficiency have gradually become a research hotspot. However, quantitative studies on nonlinear enhancement of nanoprobes have not been reported. In this work, by taking gold nanospheres as an example, the nonlinear photothermal and photoacoustic effects induced by self-assembly of metal nanoprobes are quantitatively investigated by finite element simulation, and the enhancement rule of photoacoustic effects of self-assembly nanoprobes is revealed, which lays a theoretical foundation for the construction of photoacoustic self-assembly nanoprobes with high conversion efficiency.

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中图分类号:Q631

DOI:10.3969/j.issn.1007-7146.2019.04.006

所属栏目:研究论文

基金项目:国家自然科学基金青年基金项目(61805085); 2017年度博士后创新人才支持计划项目(BX201700084); 中国博士后面上项目(2018M630961); 广东省自然科学基金博士科研启动项目(2018A030310519)。

收稿日期:2019-04-10

修改稿日期:2019-04-24

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石玉娇:华南师范大学 a.生物光子学研究院, b.激光生命科学研究所教育部重点实验室, 广州 510631
崔丹丹:华南师范大学 a.生物光子学研究院, b.激光生命科学研究所教育部重点实验室, 广州 510631

联系人作者:石玉娇(shiyuj@scnu.edu.cn)

备注:石玉娇, 博士后, 主要从事纳米尺度下的光声效应及非线性光声成像技术研究。

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引用该论文

SHI Yujiao,CUI Dandan. A Quantitative Study of the Nonlinear Enhancement of Photoacoustic Effect by Self-assembled Metal Nanoprobes Based on Finite Element Simulation[J]. Acta Laser Biology Sinica, 2019, 28(4): 330-335

石玉娇,崔丹丹. 基于有限元仿真定量探究贵金属纳米探针自组装诱导的非线性光声效应增强机制[J]. 激光生物学报, 2019, 28(4): 330-335

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