为了精确的检测眼部疾病造成的整个眼睛形状和尺寸的变化,需要对全眼深度进行高分辨率成像。光学相干层析(OCT)技术作为一种非接触、无损伤高分辨成像技术成为近年来在眼科临床检测及机理研究的有力工具。然而传统的傅里叶域光学相干断层扫描(FD-OCT)受其成像深度的限制不能实现全眼成像。随着OCT技术的发展,成像深度不断提高,近年来逐步实现了全眼OCT成像,并被成功应用于全眼参数测量的研究中。本文全面介绍了全眼FD-OCT技术的发展和应用,重点阐述了频域OCT(SD-COT)和扫描光源OCT(SS-OCT)的最新发展。研究表明,全眼OCT技术对眼睛病理变化的检测有潜在的临床应用价值,并为研究眼部调节、眼部生长以及生物统计学提供了强有力的成像方法。

Millions of people are affected by eye diseases which can affect the shape and dimensions of the whole eye.For examination of ocular accommodation and pathological changes caused by these diseases,high resolution imaging of the whole eye segments OCT system is desired.However,limited by the imaging depth,traditional Fourier Domain Optical Coherence Tomography (FD-OCT)can’t be used for real time whole eye segment imaging.In recent years,techniques for depth extended FD-OCT system especially for whole eye segment imaging has been developed.Application on eye parameters measurement and eye accommodation studies were successfully performed.In this paper,both of whole eye FD-OCT techniques and the application were reviewed.Potential clinical application of these techniques may be in the detection of the pathological changes of the whole eye,and whole eye segment FD-OCT system also provides a powerful imaging method for ophthalmic research.