激光生物学报, 2020, 29 (4): 302, 网络出版: 2020-12-30  

孕期新型冠状病毒感染妊娠结局的研究综述

A Review of Pregnancy Outcomes of Novel Coronavirus Infection during Pregnancy
作者单位
1 潍坊医学院, 潍坊 261053
2 潍坊医学院附属医院生殖医学中心, 潍坊 261031
摘要
病毒性肺炎是世界范围内人类常见病之一, 而近年由新型冠状病毒暴发引起的急性呼吸系统疾病严重威胁人类的健康。2019年12月以来, 暴发于中国武汉的2019新型冠状病毒(SARS-CoV-2)再一次引起全世界的高度关注, 被世界卫生组织(WHO)定为国际关注的突发公共卫生事件(PHEIC)。目前已经发现的可感染人的冠状病毒有7种, 其中4种冠状病毒在人群中比较常见, 致病性较低, 另外3种[严重急性呼吸综合征冠状病毒SARS-CoV(2002)、中东呼吸综合征冠状病毒MERS-CoV(2012)和SARS-CoV-2(2019)]所致疾病症状较重。孕妇作为特殊的易感人群, 一旦妊娠合并新型冠状病毒肺炎, 可能会对母胎造成影响, 但目前国内外对这方面的研究有限。为了尽可能地减少其对母胎产生不良后果, 我们应增加对这方面的研究。本文旨在通过对患有严重急性呼吸综合征(SARS)、中东呼吸综合征(MERS)和新型冠状病毒肺炎(COVID-19)的妊娠妇女的妊娠结局进行综述, 为今后其他相关新型冠状病毒感染孕妇的监督和管理做出指导, 为减少母胎死亡率及做好预防工作提供临床依据。
Abstract
Viral pneumonia is one of the common human diseases worldwide, and acute respiratory diseases caused by the outbreak of novel coronavirus in recent years seriously threaten human health. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which broke out in Wuhan, China since December 2019, once again attracts high attention, having been identified by WHO as an Public Health Emergency of International Concern. Seven coronaviruses have been found to infect humans, of which four are more common in the population and less pathogenic. The other three are caused by SARS-CoV (2002), MERS-CoV (2012) and SARS-CoV-2 (2019), symptoms of the diseases are severe. As a special susceptible population, once pregnant women suffer from pregnancy complicated with novel coronavirus pneumonia, it will theoretically affect the mother and fetus. However, at present, domestic and foreign studies on this aspect are limited. Therefore, in order to minimize the adverse consequences on the mother and fetus, it is necessary to strengthen the research on this aspect. This article reviews and analyzes the effects of novel coronavirus on different pregnancy states in first, second and third trimester through the pregnancy outcomes of pregnant women with SARS, MERS, and COVID-19 to provide guidance for the supervision and management of other related novel coronavirus infected pregnant women in the future, and provide a clinical basis for reducing maternal and fetal mortality and doing prevention work .

陈曦, 王桂丽. 孕期新型冠状病毒感染妊娠结局的研究综述[J]. 激光生物学报, 2020, 29(4): 302. CHEN Xi, WANG Guili. A Review of Pregnancy Outcomes of Novel Coronavirus Infection during Pregnancy[J]. Acta Laser Biology Sinica, 2020, 29(4): 302.

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