激光与光电子学进展, 2019, 56 (18): 181701, 网络出版: 2019-09-09
与组织微观结构相关的散射参数γ 及其测量方法 下载: 1046次
Scattering Parameter γ Related to Tissue Microstructure and Measuring Method
医用光学 组织光学 半经验模型 蒙特卡罗模拟 二阶光学参量 散射相函数 medical optics tissue optics semi-empirical model Monte Carlo simulation second-order optical parameter scattering phase function
摘要
研究了光源附近微区的漫反射率R 与收集孔径 、约化散射系数μ' s和散射相函数相关的参数γ 之间的关系。根据不同的生物组织,选取不同的散射相函数,采用Monte Carlo 模拟方法得到了光子经生物组织后的漫反射率数据,用得到的数据来验证反射率R 与无量纲的约化散射系数μ' s 之间的关系。结果表明:当μ' s <2时,R 对散射相函数的变化是敏感的,且与μ' s 呈线性关系,其斜率与γ 呈二次函数关系。光源附近微区的漫反射率R 对γ 的变化是敏感的,这为测量与生物组织微观结构相关的散射参数γ 提供了一种较为简单的方法。
Abstract
The relationship between diffuse reflectance R measured close to the source and parameter γ related to collecting aperture , reduced scattering coefficient μ's,and scattering phase function is discussed. According to different biological tissues, different scattering phase functions are selected, and the diffuse reflectance data of photons passing through biological tissues are obtained by Monte Carlo simulation. The relationship between the reflectance R and dimensionless reduced scattering coefficient μ's , where is the collection aperture of scattered light, is validated by the data obtained. It is found that when μ's < 2, R is sensitive to the change of the scattering phase function and has a linear relation with μ's . The slope of R is a quadratic function with respect to γ. Results demonstrate that the diffuse reflectance R of the micro-area near the light source is sensitive to the change of γ. This provides a simple method for measuring γ related to the microstructure of biological tissues.
李文艳, 王兴, 刘迎. 与组织微观结构相关的散射参数