目的: 探讨He-Ne激光照射联合抗生素预防对心脏起搏器植入术后切口愈合的影响。方法: 选取2013年3月至2018年10月我院永久心脏起搏器植入术患者146例, 随机分为C组(n＝73, 抗生素治疗)与L组(n＝73, He-Ne激光联合抗生素治疗)。观察比较两组临床疗效, 术后切口疼痛程度、舒适度, 术后感染率、囊袋血肿率及切口愈合时间。记录激光照射区域有无脱皮、烧伤等并发症。结果: ①两组总有效率和总显效率无统计学差异(P＞0.05)。② L组术后2、3、5、7 d切口疼痛评分均低于C组(P＜0.05)。③ L组治疗后肩背痛、排便排尿困难、睡眠质量差所占比例均低于C组(P＜0.05)。④两组囊袋血肿、囊袋感染及切口感染率无统计学差异(P＞0.05), 但L组切口愈合时间明显低于C组(P＜0.05)。⑤ L组患者未发生皮肤烧伤、水泡等严重损害。结论: He-Ne激光照射联合抗生素预防能够缩短心脏起搏器植入术后切口愈合时间, 减轻切口疼痛, 提高患者的舒适度, 安全性高。

To investigate the effect of He-Ne laser irradiation combined with antibiotic prophylaxis on postoperative incision healing after cardiac pacemaker implantation. Methods: a total of 146 patients with permanent cardiac pacemaker implantation from March 2013 to October 2018 were randomly divided into Group C (n＝73, antibiotic treatment) and group L (n＝73, He-Ne laser combined with antibiotic treatment). The clinical efficacy, postoperative incision pain, comfort, postoperative infection rate, cystic hematoma rate and incision healing time were observed and compared between the two groups. The complications such as skin peeling and burns were recorded. Results: ①There was no significant difference between the two groups in total efficiency rate and total significant efficiency (P>0.05). ②Postoperative incision pain scores in group L at 2, 3, 5 and 7 days were all lower than those of group C (P<0.05). ③After treatment, the proportion of shoulder and back pain, dysuria and poor sleep quality in group L were lower than that in group C (P<0.05). ④There were no significant difference between the two groups in hematoma, pouch infection and incision infection rate (P>0.05), but the healing time of incision in group L was significantly lower than that in group C (P<0.05). ⑤No serious skin burns, blisters or other damage occurred in group L. Conclusion: He-Ne laser irradiation combined with antibiotic prophylaxis can shorten the incision healing time after cardiac pacemaker implantation, reduce the incision pain, improve patient comfort and safety.