光学学报, 2017, 37 (5): 0511002, 网络出版: 2017-05-05
光学相干层析成像随深度变化的色散补偿方法 下载: 574次
Depth-Dependent Dispersion Compensation for Optical Coherence Tomography
成像系统 医用光学 光学相干层析成像 图像处理 色散补偿 imaging systems medical optics optical coherence tomography image processing dispersion compensation
摘要
提出一种随深度变化的色散补偿方法, 用以提升频域光学相干层析成像系统的纵向分辨率。该方法利用迭代算法计算出不同成像深度处的色散补偿系数, 通过数值计算, 得到色散补偿系数与成像深度的关系表达式, 计算出各成像深度处的色散补偿系数, 利用这些色散补偿系数消除相应深度位置处信号的高阶色散相位, 从而有针对性地对系统中参考臂与样品臂的色散失配进行补偿, 消除色散的展宽效应。理论推导和实验结果表明, 光学相干层析成像系统中, 随深度变化的色散补偿方法对各成像深度位置处的信号, 包括成像深度较深位置处的弱信号, 均可以进行有效的色散补偿, 进而得到更多的样品结构信息。
Abstract
A depth-dependent dispersion compensation method is presented to enhance the axial resolution in Fourier-domain optical coherence tomography. The dispersion compensation coefficients at different depths are calculated by an iterative algorithm, and a mathematical expression between the dispersion compensation coefficient and depth is obtained through numerical calculation. From the mathematical expression, the dispersion compensation coefficients at different depths are calculated to eliminate the high-order dispersion phase at different depths. The dispersion mismatch between the reference arm and sample arm is compensated and the broadening effect of dispersion is avoided. Theoretical derivation and experimental results in the optical coherence tomography systems show that the dispersion at different depths, including the deeper positions which have weaker signals, is effectively compensated by the depth-dependent dispersion compensation method and thus more structure informations of the sample are obtained.
潘柳华, 李中梁, 王向朝, 张向阳, 南楠, 陈艳, 王瑄, 卢宇. 光学相干层析成像随深度变化的色散补偿方法[J]. 光学学报, 2017, 37(5): 0511002. Pan Liuhua, Li Zhongliang, Wang Xiangzhao, Zhang Xiangyang, Nan Nan, Chen Yan, Wang Xuan, Lu Yu. Depth-Dependent Dispersion Compensation for Optical Coherence Tomography[J]. Acta Optica Sinica, 2017, 37(5): 0511002.