光学学报, 2019, 39 (11): 1111002, 网络出版: 2019-11-06
基于差分相位解析的复频域多普勒光学相干层析成像技术 下载: 928次
Complex Frequency Domain Doppler Optical Coherence Tomography Based on Phase Difference Resolved Technology
医用光学 光学相干层析成像 多普勒成像 差分相位 正弦相位调制 medical optics optical coherence tomography Doppler imaging phase difference sinusoidal phase modulation
摘要
基于正弦相位调制的全深度复频域光学相干层析成像技术,具有镜像抑制效果好、速度灵敏度高、能在信噪比最高的零光程差位置附近成像的优点,在多普勒成像领域得到了一系列应用。然而,该技术不适用于运动速度较高的样品。为此,提出一种基于差分相位解析的复频域多普勒光学相干层析成像技术。对二维干涉谱信号进行傅里叶变换得到干涉层析信号后,利用相邻干涉层析信号的差分相位重建复层析信号,对其进行相位解调,得到全深度层析图像和多普勒图像。仿真和实验结果表明,该技术能降低高速运动对时间频谱各分量展宽的影响,得到更加准确的多普勒相移和更大的速度探测范围。
Abstract
The full-range complex frequency domain optical coherence tomography based on sinusoidal phase modulation has the advantages of good effect on suppression of the mirror image and high velocity sensitivity with the highest signal-to-noise ratio (SNR) near the zero-path difference position. It has been widely utilized in the field of Doppler imaging. However, this technology is not suitable for the sample with high-speed motion affected by phase demodulation. In this paper, we present a novel approach, i.e., the complex frequency domain Doppler optical coherence tomography, based on phase difference resolved technology. After obtaining the interference tomography signal by Fourier transform of two-dimensional interference spectrum signal, and using the differential phase of the adjacent tomography signal to reconstruct the complex tomography signal, we obtain the full-range tomography images and Doppler images after sinusoidal phase demodulation. It is shown from the simulation and experimental results that this technique can reduce the broadening of the signal spectrum due to high-speed motion, so that more accurate Doppler phase shift and larger velocity detection range can be obtained.
陈红芩, 南楠, 张茜, 陈子阳, 蒲继雄, 佐佐木修己, 王向朝. 基于差分相位解析的复频域多普勒光学相干层析成像技术[J]. 光学学报, 2019, 39(11): 1111002. Hongqin Chen, Nan Nan, Xi Zhang, Ziyang Chen, Jixiong Pu, Sasaki Osami, Xiangzhao Wang. Complex Frequency Domain Doppler Optical Coherence Tomography Based on Phase Difference Resolved Technology[J]. Acta Optica Sinica, 2019, 39(11): 1111002.