中国激光, 2018, 45 (11): 1107002, 网络出版: 2018-11-15
基于对数补偿和动态阈值的手持式光学相干层析成像方法 下载: 664次
Handheld Optical Coherence Tomography Based on Logarithmic Compensation and Motion Threshold
医用光学 微血管 手持式 扫频光学相干断层成像 动态阈值 对数补偿 medical optics microvascular system handheld type frequency sweeping optical coherence tomography motion threshold logarithmic compensation
摘要
搭建了一套能够对人体皮下微血管进行快速成像的手持式扫频光学相干断层成像(OCT)系统,分别使用了无对数补偿的强度差分(PID)算法、有对数补偿的强度差分(LCPID)算法以及结合对数补偿及动态阈值方法的强度差分(MTPID)算法重建了血流分布图像,并对比了三种成像算法得到的微血管正面图。结果表明:LCPID算法能呈现更深层的血流信息,而MTPID算法获得了更多的血流分布细节信息和更高的图像清晰度,其优越性对OCT系统在医用光学方面的应用具有重要意义。
Abstract
A handheld swept optical coherence tomography system capable of rapidly imaging subcutaneous human microvascular is established. Three algorithms are used to reconstruct the blood flow distribution images: power intensity differential (PID) without logarithmic compensation, logarithmic-compensated power intensity differential (LCPID), and logarithmic-compensated power intensity differential with motion threshold (MTPID). Then, microvascular en-face images obtained by three imaging algorithm are compared. The results show that the LCPID algorithm can reveal deeper blood flow information, and the MTPID algorithm can get more details of the blood flow distribution and high image resolution. So, the superiority of MTPID algorithm has significance for the application of OCT system in biomedical optics.
张越, 高万荣, 张兰兰, 史伟松. 基于对数补偿和动态阈值的手持式光学相干层析成像方法[J]. 中国激光, 2018, 45(11): 1107002. Zhang Yue, Gao Wanrong, Zhang Lanlan, Shi Weisong. Handheld Optical Coherence Tomography Based on Logarithmic Compensation and Motion Threshold[J]. Chinese Journal of Lasers, 2018, 45(11): 1107002.