利用选择性光热解(SP)的三维光热作用模型, 对血管尺寸、位置和数目等血管参数对皮肤组织选择性光热解作用中光热响应规律的影响进行了理论分析和数值求解。数值结果表明, 当利用选择性光热解效应热损伤皮肤组织内的特定血管时, 假如一定区域内有其他血管存在, 则目标血管的热损伤率会受区域内其他血管的影响而减小。这个区域的大小与激光光斑大小及激光波长有关。一般来说, 当血管处于激光光斑以外或深度超过1 mm(对于585 nm激光)时, 这些血管的影响可忽略不计。

Using a 3D photo-thermal model for selective photothermolysis (SP), the effects of blood vessel parameters, such as blood vessel diameters, locations and numbers, on the photo-thermal interactions during SP were numerically studied. The numerical results show that the thermal damage rate of the targeted blood vessel would be decreased if there are other blood vessels existed in the neighboring region, the dimensions of which are determined by the diameter of laser beam and laser wavelength. Generally, if the other blood vessels are outside the laser beam, or deeper than 1 mm for 585 nm laser, their effects are neglectable. The study can be used for scheming and optimizing the clinical laser treatments.