[1] J. M. Adams, S. Cory, "The Bcl-2 apoptotic switch in cancer development and therapy," Oncogene 26 (9), 1324–1337 (2007).

[2] J. K. Brunelle, A. Letai, "Control of mitochondrial apoptosis by the Bcl-2 family," J. Cell Sci. 122(4), 437–441 (2009).

[3] F. Edlich, S. Banerjee, M. Suzuki, M. M. Cleland, D. Arnoult, C. Wang, A. Neutzner, N. Tjandra, R. J. Youle, "Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol," Cell 145(1), 104–116 (2011).

[4] M. C. Wei, W. X. Zong, E. H. Y. Cheng, T. Lindsten, V. Panoutsakopoulou, A. J. Ross, K. A. Roth, G. R. MacGregor, C. B. Thompson, S. J. Korsmeyer, "Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death," Science 292(5517), 727–730 (2001).

[5] K. G. Wolter, Y. T. Hsu, C. L. Smith, A. Nechushtan, X. G. Xi, R. J. Youle, "Movement of Bax from the cytosol to mitochondria during apoptosis," J. Cell Biol. 139(5), 1281–1292 (1997).

[6] A. Aranovich, Q. Liu, T. Collins, F. Geng, S. Dixit, B. Leber, D. W. Andrews, "Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells," Mol. Cell 45(6), 754–763 (2012).

[7] G. Hausmann, L. A. O'Reilly, R. van Driel, J. C. Beaumont, A. Strasser, J. M. Adams, D. C. Huang, "Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L)," J. Cell Biol. 149(3), 623–634 (2000).

[8] Y. T. Hsu, K. G. Wolter, R. J. Youle, "Cytosolto-membrane redistribution of Bax and Bcl-XL during apoptosis," Proc. Natl. Acad. Sci. USA 94 (8), 3668–3672 (1997).

[9] D. Nijhawan, M. Fang, E. Traer, Q. Zhong,W. Gao, F. Du, X. Wang, "Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation," Genes Dev. 17(12), 1475–1486 (2003).

[10] T. W. Sedlak, Z. N. Oltvai, E. Yang, K. Wang, L. H. Boise, C. B. Thompson, S. J. Korsmeyer, "Multiple Bcl-2 family members demonstrate selective dimerizations with Bax," Proc. Natl. Acad. Sci. USA 92 (17), 7834–7838 (1995).

[11] E. Yang, J. Zha, J. Jockel, L. H. Boise, C. B. Thompson, S. J. Korsmeyer, "Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death," Cell 80(2), 285–291 (1995).

[12] Y. T. Hsu, R. J. Youle, "Nonionic detergents induce dimerization among members of the Bcl-2 family," J. Biol. Chem. 272(21), 13829–13834 (1997).

[13] S. Y. Jeong, B. Gaume, Y. J. Lee, Y. T. Hsu, S. W. Ryu, S. H. Yoon, R. J. Youle, "Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers," EMBO J. 23(10), 2146–2155 (2004).

[14] L. P. Billen, C. L. Kokoski, J. F. Lovell, B. Leber, D. W. Andrews, "Bcl-XL inhibits membrane permeabilization by competing with Bax," PLoS Biol. 6(6), e147 (2008).

[15] T. T. Renault, O. Teijido, B. Antonsson, L. M. Dejean, S. Manon, "Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-xL: Keep your friends close but your enemies closer," Int. J. Biochem. Cell Biol. 45(1), 64–67 (2013).

[16] F. Llambi, T. Moldoveanu, S. W. Tait, L. Bouchier-Hayes, J. Temirov, L. L. McCormick, C. P. Dillon, D. R. Green, "A unified model of mammalian BCL-2 protein family interactions at the mitochondria," Mol. Cell 44(4), 517–531 (2011).

[17] B. Schellenberg, P. Wang, J. A. Keeble, R. Rodriguez-Enriquez, S. Walker, T. W. Owens, F. Foster, J. Tanianis-Hughes, K. Brennan, C. H. Streuli, A. P. Gilmore, "Bax exists in a dynamic equilibrium between the cytosol and mitochondria to control apoptotic priming," Mol. Cell 49(5), 959–971 (2013).

[18] T. T. Renault, O. Teijido, F. Missire, Y. T. Ganesan, G. Velours, H. Arokium, F. Beaumatin, R. Llanos, A. Athane, N. Camougrand, M. Priault, B. Antonsson, L. M. Dejean, S. Manon, "Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737," Int. J. Biochem. Cell Biol. 64, 136–146 (2015).

[19] F. Todt, Z. Cakir, F. Reichenbach, R. J. Youle, F. Edlich, "The C-terminal helix of Bcl-x(L) mediates Bax retrotranslocation from the mitochondria," Cell Death Differ. 20(2), 333–342 (2013).

[20] H. Dussmann, M. Rehm, C. G. Concannon, S. Anguissola, M. Wurstle, S. Kacmar, P. Voller, H. J. Huber, J. H. Prehn, "Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation," Cell Death Differ. 17(2), 278–290 (2010).

[21] R. Heim, R. Y. Tsien, "Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer," Curr. Biol. 6(2), 178–182 (1996).

[22] E. A. Jares-Erijman, T. M. Jovin, "Imaging molecular interactions in living cells by FRET microscopy," Curr. Opin. Chem. Biol. 10(5), 409–416 (2006).

[23] M. Mohsin, M. Z. Abdin, L. Nischal, H. Kardam, A. Ahmad, "Genetically encoded FRET-based nanosensor for in vivo measurement of leucine," Biosens. Bioelectron. 50, 72–77 (2013).

[24] A. K. Kenworthy, M. Edidin, "Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <1000 nm using imaging fluorescence resonance energy transfer," J. Cell Biol. 142(1), 69–84 (1998).

[25] F. S. Wouters, P. I. Bastiaens, K. W. Wirtz, T. M. Jovin, "FRET microscopy demonstrates molecular association of non-specific lipid transfer protein (nsL-TP) with fatty acid oxidation enzymes in peroxisomes," EMBO J. 17(24), 7179–7189 (1998).

[26] H. Yu, J. Zhang, H. Li, T. Chen, "Ma-PbFRET: Multiple acceptors FRET measurement based on partial acceptor photobleaching," Microsc. Microanal. 19(1), 171–179 (2013).

[27] S. Lalonde, D. W. Ehrhardt, D. Loque, J. Chen, S. Y. Rhee, W. B. Frommer, "Molecular and cellular approaches for the detection of protein-protein interactions: Latest techniques and current limitations," Plant J. 53(4), 610–635 (2008).

[28] A. D. Elder, A. Domin, G. K. Schierle, C. Lindon, J. Pines, A. Esposito, C. F. Kaminski, "A quantitative protocol for dynamic measurements of protein interactions by Forster resonance energy transfersensitized fluorescence emission," J. R. Soc. Interface 6(S1), S59–S81 (2009).

[29] L. Wang, T. Chen, J. Qu, X. Wei, "Photobleachingbased quantitative analysis of fluorescence resonance energy transfer inside single living cell," J. Fluoresc. 20(1), 27–35 (2010).

[30] H. Yu, J. Zhang, H. Li, J. Qu, T. Chen, "An empirical quantitative fluorescence resonance energy transfer method for multiple acceptors based on partial acceptor photobleaching," Appl. Phys. Lett. 100(25), 253701 (2012).

[31] L. Zhang, H. Yu, J. Zhang, T. Chen, "Binomial distribution-based quantitative measurement of multiple-acceptors fluorescence resonance energy transfer by partially photobleaching acceptor," Appl. Phys. Lett. 104(24), 243706 (2014).

[32] L. Chai, J. Zhang, L. Zhang, T. Chen, "Miniature fiber optic spectrometer-based quantitative fluorescence resonance energy transfer measurement in single living cells," J. Biomed. Opt. 20(3), 037008 (2015).

[33] T. Zimmermann, J. Rietdorf, A. Girod, V. Georget, R. Pepperkok, "Spectral imaging and linear unmixing enables improved FRET e±ciency with a novel GFP2-YFP FRET pair," FEBS Lett. 531(2), 245–249 (2002).

[34] C. Thaler, S. V. Koushik, P. S. Blank, S. S. Vogel, "Quantitative multiphoton spectral imaging and its use for measuring resonance energy transfer," Biophys. J. 89(4), 2736–2749 (2005).

[35] J. Zhang, H. Li, L. Chai, L. Zhang, J. Qu, T. Chen, "Quantitative FRET measurement using emissionspectral unmixing with independent excitation crosstalk correction," J. Microsc. 257(2), 104–116 (2015).

[36] M. Bruncko, T. K. Oost, B. A. Belli, H. Ding, M. K. Joseph, A. Kunzer, D. Martineau, W. J. McClellan, M. Mitten, S. C. Ng, P. M. Nimmer, T. Oltersdorf, C. M. Park, A. M. Petros, A. R. Shoemaker, X. Song, X. Wang, M. D. Wendt, H. Zhang, S. W. Fesik, S. H. Rosenberg, S. W. Elmore, "Studies leading to potent, dual inhibitors of Bcl-2 and BclxL," J. Med. Chem. 50(4), 641–662 (2007).

[37] N. S. Wang, M. T. Unkila, E. Z. Reineks, C. W. Distelhorst, "Transient expression of wild-type or mitochondrially targeted Bcl-2 induces apoptosis, whereas transient expression of endoplasmic reticulum-targeted Bcl-2 is protective against Bax-induced cell death," J. Biol. Chem. 276(47), 44117–44128 (2001).

[38] T. Zal, N. R. Gascoigne, "Photobleaching-corrected FRET e±ciency imaging of live cells," Biophys. J. 86(6), 3923–3939 (2004).

[39] H. Chen, H. L. Puhl, S. V. Koushik, S. S. Vogel, S. R. Ikeda, "Measurement of FRET e±ciency and ratio of donor to acceptor concentration in living cells," Biophys. J. 91(5), L39–L41 (2006).