目的: 观察光子中医信息疗法对糖尿病周围神经病变患者的临床疗效。方法: 将60例符合入选标准的患者, 以1∶1的比例随机分配到治疗组(光子中医信息疗法联合药物组)、对照组(药物组), 两组患者均给予糖尿病基础治疗, 对照组加甲钴胺口服, 每次500 μg, 每日3次, 疗程4周; 治疗组在对照组的基础上配合光子中医信息疗法, 隔日照射1次, 每周3次, 6次为1疗程, 共2个疗程。治疗前后分别对两组患者的中医临床症状、神经症状体征进行评定, 并测定周围神经传导速度及观察血糖变化情况, 进行综合疗效评估。结果: 治疗组的临床综合疗效明显优于对照组, 两组的总有效率比较有显著性差异(P<0.05)。治疗组在中医症状改善、周围神经症状及体征改善、提高周围神经传导速度方面均优于对照组, 组间比较均具有显著性差异(P<0.05)。治疗后治疗组空腹血糖、餐后血糖、糖化血红蛋白与治疗前比较均明显降低(P<0.01), 对照组治疗前后比较及治疗后组间比较均无显著性差异(P>0.05)。结论: 光子中医信息疗法联合药物组相对于药物组在改善DPN患者的临床症状、周围神经症状及体征、神经的传导速度等方面均有良好的优势, 同时具有一定的辅助降糖趋势。

Objective: To observe the clinical therapeutic efficacy of the photonic traditional Chinese medicine information therapeutics in the treatment of diabetic peripheral neuropathy (DPN). Methods: 60 DPN patients meeting the inclusion criteria were randomly grouped to treatment group which involved the photonic TCM information therapeutics plus medical therapy and control group with medical therapy alone in 1∶1 ratio by order of treatment. On the basis of conventional treatment for diabetes mellitus, control group used western medicine Methycobal, 500 μg, 3 times a day for 4 weeks; while treatment group used the treatment of control group plus photonic Traditional Chinese Medicine information therapeutics, once every two days, 3 times a week and continuously for 4 weeks. Patients’clinical symptoms, neurological symptoms and signs, the peripheral nerve conduction velocity and blood glucose were measured before and after treatment to evaluate the comprehensive therapeutic effects. Results: The clinical comprehensive therapeutic effects of the treatment group was significantly superior to the control group (P<0.05).The improvement of TCM symptoms, neurological symptoms and nerve conduction velocity of the treatment group were significantly superior to the control group (P<0.05). Within group comparison showed that FBG, 2 h PBG, HbAlc of treatment group after treatment were all reduced significantly(P<0.01), while those of control were not reduced significantly(P>0.05); Between groups comparison showed that the changes of those indexes after treatment between groups had no significant difference(P>0.05).Conclusion: The photonic TCM information therapeutics combined with methycobal not only has some advantage compared with the control group in improving DPN patients’ TCM symptoms, peripheral nerve symptoms and signs, nerve conduction velocity, but also has a certain auxiliary hypoglycemic trend.