中国激光, 2018, 45 (2): 0207005, 网络出版: 2018-03-28
生物组织黏弹性激光散斑检测方法研究进展 下载: 1406次特邀综述
Viscoelasticity Measurement of Biological Tissues Using Laser Speckle Techniques: a Review
生物医学 黏弹性 激光散斑 光学检测 生物组织 biotechnology viscoelasticity laser speckle optical measurement biological tissue
摘要
生物组织的黏性和弹性在许多疾病发生和发展的过程中会发生改变,因此检测生物组织黏弹性对疾病诊疗具有重要意义。基于此,介绍了基于激光散斑技术的生物组织黏弹性测量方法。从弹性波调制下的激光散斑衬比变化,布朗运动下的光强自相关函数和低频交变应力作用下的散斑位移3个方面,分别介绍生物组织黏弹性激光散斑检测的理论基础和研究现状。
Abstract
Viscosity and elasticity of biological tissues will change during onset and progression of many diseases. Viscoelasticity measurement of biological tissues plays an important role in diagnosis of diseases. We particularly review some basic principles and recent advances of viscoelasticity measurement based on laser speckle techniques from three aspects: difference of laser speckle contrast under elastic waves, optical intensity autocorrelation curve under Brownian motion, and laser speckle shift under low frequency oscillation stress.
陈肖, 陆锦玲, 李鹏程. 生物组织黏弹性激光散斑检测方法研究进展[J]. 中国激光, 2018, 45(2): 0207005. Chen Xiao, Lu Jinling, Li Pengcheng. Viscoelasticity Measurement of Biological Tissues Using Laser Speckle Techniques: a Review[J]. Chinese Journal of Lasers, 2018, 45(2): 0207005.