光学技术, 2018, 44 (3): 287, 网络出版: 2018-06-09   

测量葡萄糖浓度的光学低相干干涉法

The measurement of the concentration of glucose solution by using optical low coherence interferometry
作者单位
上海理工大学 教育部微创医疗器械工程研究中心, 上海 200093
摘要
根据溶液中溶质的浓度变化将引起溶液折射率变化的特性, 提出一种利用光学低相干干涉技术通过测量葡萄糖溶液的折射率来确定其浓度的方法。基于迈克尔逊干涉仪, 建立了低相干光葡萄糖浓度检测系统, 通过调节可移动角镜以产生干涉信号, 根据角镜的位移量计算出光程, 并进而求出折射率。实验结果表明: 在LED光源光谱半高宽度为25nm, 可移动角镜的移动步长为微米量级时, 利用该方法对折射率的测量精度可以达到10-4数量级以上, 对应的可以检测出低于100mg/dL的葡萄糖的浓度变化。过程方便快捷, 受外界限制因素小, 是一种有效的测量各种液体折射率及浓度的方法。
Abstract
The change of the concentration in solution will cause the change of refractive index of the solution. In this paper, the optical low coherence technology is used to measure the refractive index of glucose solution, and then the concentration of glucose solution can be determined from the refractive index. Putting the solution into the measuring optical path, the optical path length difference can be measured from the interference signals obtained from the photodetector, and then the refractive index of the glucose solution and concentration can be calculated. The experimental results show that the refractive index measurement precision can reach 10-4 orders of magnitude, when the LED light source is used with the Full Width at Half Maximum (FWHM) of 25 nanometers and the portable corner mirror is used with micron moving step. Using the method the glucose concentrations of less than 100 mg/dL can also be measured. The process is convenient and small restricted by external factors. And the effective method can be applied to measure liquid refractive index and concentration.

张浩, 陈明惠, 李振洋, 王成, 郑刚. 测量葡萄糖浓度的光学低相干干涉法[J]. 光学技术, 2018, 44(3): 287. ZHANG Hao, CHEN Minghui, LI Zhenyang, WANG Cheng, ZHENG Gang. The measurement of the concentration of glucose solution by using optical low coherence interferometry[J]. Optical Technique, 2018, 44(3): 287.

本文已被 2 篇论文引用
被引统计数据来源于中国光学期刊网
引用该论文: TXT   |   EndNote

相关论文

加载中...

关于本站 Cookie 的使用提示

中国光学期刊网使用基于 cookie 的技术来更好地为您提供各项服务,点击此处了解我们的隐私策略。 如您需继续使用本网站,请您授权我们使用本地 cookie 来保存部分信息。
全站搜索
您最值得信赖的光电行业旗舰网络服务平台!