Label-free sensing of ultralow-weight molecules with all-dielectric metasurfaces supporting bound states in the continuum
The realization of an efficient optical sensor based on a photonic crystal metasurface supporting bound states in the continuum is reported. Liquids with different refractive indices, ranging from 1.4000 to 1.4480, are infiltrated in a microfluidic chamber bonded to the sensing dielectric metasurface. A bulk liquid sensitivity of 178 nm/RIU is achieved, while a Q-factor of about 2000 gives a sensor figure of merit up to 445 in air at both visible and infrared excitations. Furthermore, the detection of ultralow-molecular-weight (186 Da) molecules is demonstrated with a record resonance shift of 6 nm per less than a 1 nm thick single molecular layer. The system exploits a normal-to-the-surface optical launching scheme, with excellent interrogation stability and demonstrates alignment-free performances, overcoming the limits of standard photonic crystals and plasmonic resonant configurations.
Gianluigi Zito：Institute of Protein Biochemistry, National Council of Research, Via Pietro Castellino, 80131 Naples, Italy
Stefania Torino：Institute for Microelectronics and Microsystems, Unit of Naples, National Council of Research, Via Pietro Castellino, 80131 Naples, Italy
Giuseppe Calafiore：Lawrence Berkeley National Laboratory, Molecular Foundry Division, 67 Cyclotron Road, Berkeley, California 94720, USA
Erika Penzo：Lawrence Berkeley National Laboratory, Molecular Foundry Division, 67 Cyclotron Road, Berkeley, California 94720, USA
Giuseppe Coppola：Institute for Microelectronics and Microsystems, Unit of Naples, National Council of Research, Via Pietro Castellino, 80131 Naples, Italy
Stefano Cabrini：Lawrence Berkeley National Laboratory, Molecular Foundry Division, 67 Cyclotron Road, Berkeley, California 94720, USA
Ivo Rendina：Institute for Microelectronics and Microsystems, Unit of Naples, National Council of Research, Via Pietro Castellino, 80131 Naples, Italy
Vito Mocella：Institute for Microelectronics and Microsystems, Unit of Naples, National Council of Research, Via Pietro Castellino, 80131 Naples, Italy
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Silvia Romano, Gianluigi Zito, Stefania Torino, Giuseppe Calafiore, Erika Penzo, Giuseppe Coppola, Stefano Cabrini, Ivo Rendina, and Vito Mocella, "Label-free sensing of ultralow-weight molecules with all-dielectric metasurfaces supporting bound states in the continuum," Photonics Research 6(7), 726-733 (2018)