应用激光, 2019, 39 (1): 180, 网络出版: 2019-04-16   

Er:YAG激光应用于慢性牙周炎治疗的临床疗效meta分析

The Effects of Er:YAG Laser Therapy in the Treatment of Chronic Periodontitis: A Meta-Analysis
作者单位
重庆医科大学附属口腔医院, 口腔疾病与生物医学重庆市重点实验室, 重庆市高校市级口腔生物医学工程重点实验室, 重庆 401147
摘要
目的: 运用循证医学的方法系统地评价, Er:YAG激光相较于传统龈下刮治及根面平整术(Scaling and root planing, SRP)在治疗慢性牙周炎(Chronic periodontitis, CP)中的临床疗效。方法: 检索PubMed、EMbase、The Cochrane Library、中国知网、维普、万方等电子数据库, 收集自建库到2018年9月公开发表的关于Er:YAG激光与单独使用SRP比较, 用于治疗CP的临床随机对照试验。由2名研究员按照纳入和排除标准独立筛选文献、质量评价和数据提取, 使用Revman5.3.3软件进行统计分析。结果: 共纳入11篇RCT, meta结果显示短中期内, 应用Er:YAG激光与单独使用SRP治疗CP相比, 其牙周探诊深度(Periodontal probing depth, PPD)差异无统计学意义[MD=0.05, 95% CI(-0.01, 0.12), P=0.12], 而临床附着丧失水平(Clinical attach loss, CAL)在治疗后3个月, SRP组优于Er:YAG激光组[MD=0.13, 95% CI(0.02, 0.24), P=0.02], 6个月时, 两组差异无统计学意义。结论: 现有证据显示, 与传统SRP相比, Er:YAG激光在短中期临床疗效上尚不能体现出明显的治疗优势。
Abstract
Objective: to assess the clinical efficacy of Er:YAG laser compared with traditional scaling and root planing (SRP) in the treatment of chronic periodontitis (CP) by evidence-based medicine. Methods: Electronic databases including PubMed, EMbase, The Cochrane Library, CNKI, VIP data and Wanfang data were searched to collect literatures which are randomized controlled trials of Er:YAG laser and SRP alone for the treatment of CP from establishment to September 2018. Two researchers independently screened the literature, quality evaluation and data extraction in accordance with inclusion and exclusion criteria, and Revman5.3.3 software was applied for statistical analysis. Results: a total of 11 RCTs were included. The meta results showed no significant difference in periodontal probing depth (PPD) between the Er:YAG laser and the SRP alone[MD=0.05, 95% CI(-0.01, 0.12), P=0.12), and clinical attachment loss (CAL), SRP group was superior to Er:YAG laser group [MD=0.13, 95% CI(0.02,0.24), P=0.02], 3 months after treatment. There was no statistically significant difference between the two groups after 6 months. Conclusion: the existing evidence shows that Er:YAG laser has no obvious therapeutic advantage compared with traditional SRP in short-term and medium-term clinical efficacy.

张奕, 李永凯, 潘兰兰, 李静, 刘秋月, 向学熔. Er:YAG激光应用于慢性牙周炎治疗的临床疗效meta分析[J]. 应用激光, 2019, 39(1): 180. Zhang Yi, Li Yongkai, Pan Lanlan, Li Jing, Liu Qiuyue, Xiang Xuerong. The Effects of Er:YAG Laser Therapy in the Treatment of Chronic Periodontitis: A Meta-Analysis[J]. APPLIED LASER, 2019, 39(1): 180.

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