采用真空蒸镀法与湿法转移法制备出银/石墨烯/银(AG/GE/AG)三层结构,再通过一次高温退火,获得可重复利用的AG/GE/AG复合结构基底。利用COMSOL Multiphysics仿真软件计算了电场分布和理论增强因子。拉曼测试实验表明:对基底进行拉曼mapping测试,石墨烯D、G和二维峰的相对标准偏差(RSD)值分别为26.0%、17.8%和23.6%,说明基底均匀性较好。对罗丹明6G(R6G)和结晶紫(CV)的检测极限低至10 -7 mol/L。以浓度为10 -5 mol/L的R6G作为探针分子,硼氢化钠溶液作为清洗剂,研究了AG/GE/AG基底的重复性实验。以613 cm -1和773 cm -1处拉曼峰为例,清洗后,拉曼强度分别维持在71.08%和71.60%。

The three-layer structure of silver/graphene/silver (AG/GE/AG) was prepared by vacuum evaporation method and wet transfer method, and then through a high temperature annealing, a reusable AG/GE/AG composite structure substrate was obtained. The electric field distribution and theoretical enhancement factor were calculated using COMSOL Multiphysics simulation software. The Raman measurements show that the relative standard deviation (RSD) values of the D, G, and two-dimensional peaks of graphene are 26.0%, 17.8%, and 23.6%, respectively, indicating its good uniformity. The detection limits for rhodamine 6G (R6G) and crystal violet (CV) are as low as 10 ^-7 mol/L. Using R6G with a concentration of 10 ^-5 mol/L as the probe molecule and sodium borohydride solution as the cleaning agent, the repeatability experiment of AG/GE/AG substrate was studied. Taking Raman peaks at 613 cm ^-1and 773 cm ^-1 as examples, the Raman intensity was maintained at 71.08% and 71.60%, respectively.