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摘要

Photoacoustic (PA) microscopy comes with high potential for human skin imaging, since it allows noninvasively high-resolution imaging of the natural hemoglobin at depths of several millimeters. Here, we developed a PA microscopy to achieve high-resolution, high-contrast, and large field of view imaging of skin. A three-dimensional (3D) depth-coding technology was used to encode

PDF全文 Chinese Optics Letters | 2018,16(08):081701
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0 48 171

摘要

Blood oxygenation and flow are both important parameters in a living body. In this Letter, we introduce a simple configuration to simultaneously measure blood flow and oxygenation using an off-the-shelf spectrometer. With the integration time of 10 ms, flow phantom measurements, a liquid blood phantom test, and an arm cuff occlusion paradigm were performed to validate the feasi

PDF全文 Chinese Optics Letters | 2018,16(07):071701
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0 53 150

摘要

Photoacoustic imaging (PAI) has been used to characterize the spatial and quantitative features of lipid-rich atherosclerotic plaques with high sensitivity and specificity. In this Letter, we first validate that the ultra-low temperature and formaldehyde treatment have no effect on photoacoustic characteristics of the artery samples. Comparative experiments between the PAI and

PDF全文 Chinese Optics Letters | 2018,16(03):031702
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0 129 397

摘要

We demonstrate a system for measuring the ocular axial length (AL) with high sensitivity and high speed using spectral-domain low-coherence interferometry (SD-LCI). To address the limit in measuring such a large range by using SD-LCI, we propose a full-range method to recognize the positive and negative depths. The reference arm length is changed synchronously with the shift of

PDF全文 Chinese Optics Letters | 2018,16(03):031701
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0 90 241

摘要

We develop an improved global reconstruction method for Fourier ptychographic microscopy, a newly reported technique for wide-field and high-resolution microscopic observation. The gradational strategy and graphic processing unit computing are applied to accelerate the conventional global reconstruction method. Both simulations and experiments are carried out to evaluate the pe

PDF全文 Chinese Optics Letters | 2017,15(11):111702
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0 209 496

摘要

We experimentally demonstrate a metamaterials (MMs)-based terahertz (THz) sensor to quickly distinguish the cancer tissues from normal tissues. The MMs-based THz sensor has two strong resonance absorption peaks at about 0.706 and 1.14 THz, respectively. When the sensor is covered with cancer tissues, the redshifts at about 0.706 and 1.14 THz are 31 and 19 GHz, respectively. How

PDF全文 Chinese Optics Letters | 2017,15(11):111703
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0 301 825

摘要

Photoacoustic tomography is a noninvasive and nonionized biomedical imaging modality but it cannot reveal the inner structure and sideward boundary information of blood vessels in the linear array detection mode. In contrast, Monte Carlo (MC) light transport could provide the optical fluence distribution around the entire vascular area. This research explores the combination of

PDF全文 Chinese Optics Letters | 2017,15(11):111701
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0 242 564

摘要

An endoscopic imaging system using a plenoptic technique to reconstruct 3-D information is demonstrated and analyzed in this Letter. The proposed setup integrates a clinical surgical endoscope with a plenoptic camera to achieve a depth accuracy error of about 1 mm and a precision error of about 2 mm, within a 25 mm×25 mm field of view, operating at 11 frames per second.

PDF全文 Chinese Optics Letters | 2017,15(05):051701
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0 506 1009

摘要

As a high-resulotion biological imaging technology, photoacoustic microscopy (PAM) is difficult to use in real-time imaging due to the long data acquisition time. Herein, a fast data acquisition and image recovery method named sparse PAM based on a low-rank matrix approximation is proposed. Specifically, the process to recover the final image from incomplete data is formulated

PDF全文 Chinese Optics Letters | 2016,14(09):091701
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0 510 1089

摘要

Brain regenerative studies require precise visualization of the morphological structures. However, few imaging methods can effectively detect the adult zebrafish brain in real time with high resolution and good penetration depth. Long-term in vivo monitoring of brain injuries and brain regeneration on adult zebrafish is achieved in this study by using 1325 nm spectral-domain op

PDF全文 Chinese Optics Letters | 2016,14(08):081702
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0 343 750
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